EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural States of ROR gamma t: X-ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds.
ジャーナル・号・ページ	ChemMedChem, Vol. 12, Page 1014-1021, Year 2017
掲載日	2017年4月28日 (構造データの登録日)
著者	Kallen, J. / Izaac, A. / Be, C. / Arista, L. / Orain, D. / Kaupmann, K. / Guntermann, C. / Hoegenauer, K. / Hintermann, S.
リンク	ChemMedChem / PubMed:28590087
手法	X線回折
解像度	1.64 - 2.4 Å
構造データ	PDB-5nti: Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-5ntk: Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-5ntn: Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-5ntp: Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-5ntq: Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds 手法: X-RAY DIFFRACTION / 解像度: 2.26 Å PDB-5ntw: Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds 手法: X-RAY DIFFRACTION / 解像度: 1.64 Å PDB-5nu1: Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å
化合物	ChemComp-C3S: CHOLEST-5-EN-3-YL HYDROGEN SULFATE / コレステロ-ル硫酸 ChemComp-HOH: WATER ChemComp-99N: [(3~{S},8~{S},9~{S},10~{R},13~{R},14~{S},17~{R})-10,13-dimethyl-17-[(2~{R})-5-[[4-(2-morpholin-4-ylethoxy)phenyl]methylamino]-5-oxidanylidene-pentan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate ChemComp-98H: (5R,10S,13R,14R,17R)-17-((R,E)-7-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethyl-1,2,5,6,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-3,7(4H)-dione / ガノデロンA ChemComp-98E: (S)-N-(5-chloro-3-((4-(cyclopentanecarbonyl)-3-methylpiperazin-1-yl)methyl)-2-methylphenyl)-2-methylpyrimidine-5-carboxamide ChemComp-444: N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE / T-0901317 ChemComp-98N: (S)-N-((5-(ethylsulfonyl)pyridin-2-yl)methyl)-7-isopropyl-6-(((1r,4S)-4-(trifluoromethyl)cyclohexyl)methyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-3-carboxamide ChemComp-8YB: ~{N}-[4-(3-chlorophenyl)-5-(2-chlorophenyl)carbonyl-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)ethanamide / N-[4-(3-クロロフェニル)-5-(2-クロロベンゾイル)チアゾ-ル-2-イル]-2-[4-(エチルスルホニル)フ(以下略)
由来	homo sapiens (ヒト)
キーワード	SIGNALING PROTEIN / nuclear hormone receptor / ligand-binding domain / agonist / NUCLEAR PROTEIN / inverse agonist