EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	A crystallographic fragment study with cAMP-dependent protein kinase A
ジャーナル・号・ページ	To Be Published
掲載日	2016年11月24日 (構造データの登録日)
著者	Siefker, C. / Heine, A. / Klebe, G.
リンク	PubMedで検索
手法	X線回折
解像度	1.12 - 1.833 Å
構造データ	PDB-5mhi: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule (5-chloro-2-methoxyphenyl)methanamine 手法: X-RAY DIFFRACTION / 解像度: 1.489 Å PDB-5n1d: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule N-methyl-1-(5-pyridin-3-yloxyfuran-2-yl)methanamine 手法: X-RAY DIFFRACTION / 解像度: 1.609 Å PDB-5n1e: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule N-(1,3-benzodioxol-5-yl)-2-piperidin-1-ylacetamide 手法: X-RAY DIFFRACTION / 解像度: 1.529 Å PDB-5n1f: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule N-quinolin-5-ylpyridine-3-carboxamide 手法: X-RAY DIFFRACTION / 解像度: 1.12 Å PDB-5n1g: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 4-(2-Amino-1,3-thiazol-4-yl)-1-oxaspiro[4.5]decan-2-one 手法: X-RAY DIFFRACTION / 解像度: 1.14 Å PDB-5n1h: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule Methyl 4-(aminomethyl)benzoate 手法: X-RAY DIFFRACTION / 解像度: 1.18 Å PDB-5n1k: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 2-amino-1-(4-fluorophenyl)ethanol 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-5n1l: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 2,5-dimethyl-N-pyridin-4-ylfuran-3-carboxamide 手法: X-RAY DIFFRACTION / 解像度: 1.489 Å PDB-5n1m: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule (5-chloro-2-methoxyphenyl)methanamine 手法: X-RAY DIFFRACTION / 解像度: 1.436 Å PDB-5n1n: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 2-chloro-9-propan-2-ylpurine 手法: X-RAY DIFFRACTION / 解像度: 1.405 Å PDB-5n1o: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 2-chloro-4-(chloromethyl)-5-hydroxyphenyl)ethan-1-one 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-5n32: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 4-chlorobenzyl carbamimidothioate 手法: X-RAY DIFFRACTION / 解像度: 1.833 Å PDB-5n36: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 3H-isoindol-2-ium-1-amine 手法: X-RAY DIFFRACTION / 解像度: 1.58 Å PDB-5n37: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule N-(1,3-benzodioxol-5-ylmethyl)cyclopentanamine 手法: X-RAY DIFFRACTION / 解像度: 1.589 Å PDB-5n39: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)pyrrolidine 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-5n3a: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 4-methyl-5-(1-methylimidazol-2-yl)-1,3-thiazol-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.404 Å PDB-5n3b: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 2-(pyridin-3-yl)ethanamine 手法: X-RAY DIFFRACTION / 解像度: 1.64 Å PDB-5n3f: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule N-[3-(aminomethyl)phenyl]acetamide 手法: X-RAY DIFFRACTION / 解像度: 1.68 Å PDB-5n3g: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule (R)-1,4-oxazepan-6-ol 手法: X-RAY DIFFRACTION / 解像度: 1.16 Å PDB-5n3i: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule methyl (2S)-2-amino-3-phenylpropanoate 手法: X-RAY DIFFRACTION / 解像度: 1.14 Å PDB-5n3k: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule O-guanidino-L-homoserine 手法: X-RAY DIFFRACTION / 解像度: 1.33 Å PDB-5n3l: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol 手法: X-RAY DIFFRACTION / 解像度: 1.38 Å PDB-5n3m: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule D-arginine 手法: X-RAY DIFFRACTION / 解像度: 1.229 Å PDB-5n3n: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule [(2R)-2,4-dihydroxy-4-oxobutyl]-trimethylazanium 手法: X-RAY DIFFRACTION / 解像度: 1.224 Å PDB-5n3o: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 3-(1,3-oxazol-5-yl)aniline 手法: X-RAY DIFFRACTION / 解像度: 1.32 Å PDB-5n3p: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 1H-Indol-5-ol 手法: X-RAY DIFFRACTION / 解像度: 1.58 Å PDB-5n3r: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 2-(carbamoylamino)-4-methylsulfanylbutanoic acid 手法: X-RAY DIFFRACTION / 解像度: 1.36 Å PDB-5n3t: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 5-Chlorothiophene-2-sulfonamide 手法: X-RAY DIFFRACTION / 解像度: 1.209 Å PDB-5n7p: cAMP-dependent Protein Kinase A from Cricetulus griseus in complex with fragment like molecule 3-amino-5-(pyrrolidin-1-yl)-1H-pyrazole-4-carbonitrile 手法: X-RAY DIFFRACTION / 解像度: 1.501 Å
化合物	ChemComp-MPD: (4S)-2-METHYL-2,4-PENTANEDIOL / (S)-2-メチル-2,4-ペンタンジオ-ル / 沈殿剤YM ChemComp-7N9: (5-chloranyl-2-methoxy-phenyl)methylazanium ChemComp-DMS: DIMETHYL SULFOXIDE / 2-チアプロパン2-オキシド / DMSO, 沈殿剤YM ChemComp-HOH: WATER ChemComp-8FZ: (5-pyridin-3-yloxyfuran-2-yl)methanamine ChemComp-9NT: ~{N}-(1,3-benzodioxol-5-yl)-2-piperidin-1-ium-1-yl-ethanamide ChemComp-8ET: ~{N}-quinolin-5-ylpyridine-3-carboxamide ChemComp-MRD: (4R)-2-METHYLPENTANE-2,4-DIOL / (4R)-2-メチル-2,4-ペンタンジオ-ル / 沈殿剤YM ChemComp-8G5: (4R)-4-(2-amino-1,3-thiazol-4-yl)-1-oxaspiro[4.5]decan-2-one ChemComp-8G2: (4-methoxycarbonylphenyl)methylazanium / 4-(アミニオメチル)安息香酸メチル ChemComp-489: (1S)-2-amino-1-(4-fluorophenyl)ethanol / (S)-1-(4-フルオロフェニル)-2-アミノエタノ-ル ChemComp-47V: 2,5-dimethyl-N-(pyridin-4-yl)furan-3-carboxamide ChemComp-BJK: (4-methoxy-3-oxidanyl-phenyl)methylazanium ChemComp-8G8: 2-chloranyl-9-methyl-purine ChemComp-8GB: 1-[5-chloranyl-3-(chloromethyl)-2-oxidanyl-phenyl]ethanone ChemComp-8K5: [azanyl-[(4-chlorophenyl)methylsulfanyl]methylidene]azanium / ジアミノ[(4-クロロフェニルメチル)チオ]メチリウム ChemComp-F05: 1H-isoindol-3-amine / イソインドリン-1-イミン ChemComp-8JT: 1,3-benzodioxol-5-ylmethyl(cyclopentyl)azanium ChemComp-8LZ: (2~{S})-2-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrrolidin-1-ium ChemComp-46P: 4-methyl-5-(1-methyl-1H-imidazol-2-yl)-1,3-thiazol-2-amine ChemComp-BJN: 2-pyridin-3-ylethylazanium ChemComp-463: N-[3-(aminomethyl)phenyl]acetamide ChemComp-8KB: (6~{R})-1,4-oxazepan-6-ol ChemComp-BJQ: [(2~{S})-1-methoxy-1-oxidanylidene-3-phenyl-propan-2-yl]azanium / (L-フェニルアラニンメチル)-N-カチオン ChemComp-GGB: L-CANAVANINE / カナバニン ChemComp-E5E: Noradrenaline / (R)-2-(3,4-ジヒドロキシフェニル)-2-ヒドロキシエタンアミニウム / 神経伝達物質, ホルモンYM ChemComp-DAR: D-ARGININE ChemComp-152: CARNITINE / カルニチン ChemComp-5AO: 3-(1,3-oxazol-5-yl)aniline / 3-(5-オキサゾリル)アニリン ChemComp-5H1: 1H-indol-5-ol / 5-ヒドロキシインド-ル ChemComp-CDT: 4-METHYLSULFANYL-2-UREIDO-BUTYRIC ACID / N-カルバモイル-D-メチオニン ChemComp-8K2: 5-chloranylthiophene-2-sulfonamide / 5-クロロチオフェン-2-スルホンアミド ChemComp-E9Q: 5-azanyl-3-pyrrolidin-1-yl-1~{H}-pyrazole-4-carbonitrile
由来	cricetulus griseus (モンゴルキヌゲネズミ)
キーワード	TRANSFERASE / fragment / complex / serine threonine kinase / cAMP / kinase / PKA / serine threonine kinas / kinse