EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.
ジャーナル・号・ページ	ACS Chem. Biol., Vol. 11, Page 3093-3105, Year 2016
掲載日	2016年9月5日 (構造データの登録日)
著者	Tisi, D. / Chiarparin, E. / Tamanini, E. / Pathuri, P. / Coyle, J.E. / Hold, A. / Holding, F.P. / Amin, N. / Martin, A.C. / Rich, S.J. ...Tisi, D. / Chiarparin, E. / Tamanini, E. / Pathuri, P. / Coyle, J.E. / Hold, A. / Holding, F.P. / Amin, N. / Martin, A.C. / Rich, S.J. / Berdini, V. / Yon, J. / Acklam, P. / Burke, R. / Drouin, L. / Harmer, J.E. / Jeganathan, F. / van Montfort, R.L. / Newbatt, Y. / Tortorici, M. / Westlake, M. / Wood, A. / Hoelder, S. / Heightman, T.D.
リンク	ACS Chem. Biol. / PubMed:27571355
手法	X線回折
解像度	1.51 - 2.9 Å
構造データ	PDB-5lss: Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 手法: X-RAY DIFFRACTION / 解像度: 1.79 Å PDB-5lsu: Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 手法: X-RAY DIFFRACTION / 解像度: 2.14 Å PDB-5lsx: Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-5lsy: Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-5lsz: Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-5lt6: Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 手法: X-RAY DIFFRACTION / 解像度: 2.05 Å PDB-5lt7: Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 手法: X-RAY DIFFRACTION / 解像度: 1.51 Å PDB-5lt8: Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives 手法: X-RAY DIFFRACTION / 解像度: 1.57 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-SCN: THIOCYANATE ION / チオシアン酸アニオン ChemComp-76H: [(2~{S},5~{R})-1-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]-5-azaniumyl-6-oxidanyl-6-oxidanylidene-hexan-2-yl]-propyl-azanium ChemComp-HOH: WATER ChemComp-SAM: S-ADENOSYLMETHIONINE ChemComp-76O: [(2~{R},5~{S})-1-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]-5-azaniumyl-6-oxidanyl-6-oxidanylidene-hexan-2-yl]-(phenylmethyl)azanium ChemComp-76M: [(2~{S},5~{R})-1-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]-5-azaniumyl-6-oxidanyl-6-oxidanylidene-hexan-2-yl]-(2-methylpropyl)azanium ChemComp-76K: [(2~{S},5~{R})-1-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]-5-azaniumyl-6-oxidanyl-6-oxidanylidene-hexan-2-yl]-(3-oxidanylpropyl)azanium ChemComp-76J: [(2~{S},5~{S})-1-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]-5-azaniumyl-6-oxidanyl-6-oxidanylidene-hexan-2-yl]-pentyl-azanium ChemComp-76L: [(2~{S},5~{R})-1-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]-5-azaniumyl-6-oxidanyl-6-oxidanylidene-hexan-2-yl]-[(2~{R})-2-oxidanylpropyl]azanium ChemComp-SFG: SINEFUNGIN / シネフンギン
由来	homo sapiens (ヒト)
キーワード	TRANSFERASE / lysine methyltransferase / MMSET / SETD2 / SET domain / SETD2#1 / lysine methyltransferase MMSET SET domain / lysine methyltransferase SETD2 SET domain