EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
ジャーナル・号・ページ	Science, Vol. 352, Page 1334-1337, Year 2016
掲載日	2016年6月12日 (構造データの登録日)
著者	Gao, Y. / Yang, W.
リンク	Science / PubMed:27284197
手法	X線回折
解像度	1.44 - 1.9 Å
構造データ	PDB-5kfa: Human DNA polymerase eta-DNA ternary complex: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion 手法: X-RAY DIFFRACTION / 解像度: 1.51 Å PDB-5kfb: Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 90s 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-5kfc: Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 180s 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-5kfd: Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 300s 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-5kfe: Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 600s 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-5kff: Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 1800s 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-5kfg: Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 30s 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-5kfh: Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 90s 手法: X-RAY DIFFRACTION / 解像度: 1.72 Å PDB-5kfi: Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 120s 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-5kfj: Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 180s 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-5kfk: Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 300s 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-5kfl: Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 600s 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-5kfm: Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-5kfn: Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 1 mM Mg2+ for 1800s 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-5kfo: Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 1 mM Mn2+ for 1800s 手法: X-RAY DIFFRACTION / 解像度: 1.52 Å PDB-5kfp: Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 20 mM Mg2+ for 600s 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-5kfq: Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 10 mM Mn2+ for 600s 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-5kfr: Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 20 mM Mn2+ for 600s 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-5kfs: Human DNA polymerase eta R61A-DNA ternary complex: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion 手法: X-RAY DIFFRACTION / 解像度: 1.46 Å PDB-5kft: Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 40s 手法: X-RAY DIFFRACTION / 解像度: 1.52 Å PDB-5kfu: Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 80s 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-5kfv: Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 140s 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-5kfw: Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 200s 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-5kfx: Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 300s 手法: X-RAY DIFFRACTION / 解像度: 1.52 Å PDB-5kfy: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 4 degree 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-5kfz: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 14 degree 手法: X-RAY DIFFRACTION / 解像度: 1.44 Å PDB-5kg0: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 22 degree 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-5kg1: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 30 degree 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-5kg2: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 37 degree 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-5kg3: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Mn2+ for 60s 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-5kg4: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Mg2+ for 60s 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-5kg5: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Cd2+ for 60s 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-5kg6: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Ca2+ for 60s 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-5kg7: Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Zn2+ for 60s 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-5l9x: Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 60s 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å
化合物	ChemComp-CA: Unknown entry / カルシウムジカチオン ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-DTP: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE / dATP ChemComp-K: Unknown entry / カリウムカチオン ChemComp-HOH: WATER ChemComp-MN: Unknown entry ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-DPO: DIPHOSPHATE / ジホスファ-ト ChemComp-STP: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE) ChemComp-MG: Unknown entry / マグネシウムジカチオン
由来	homo sapiens (ヒト)
キーワード	REPLICATION / TRANSFERASE/DNA / in crystallo reaction / DNA polymerase / metal ion dependent catalysis / TRANSFERASE-DNA complex / TRANSFERASE