EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors.
ジャーナル・号・ページ	Biochemistry, Vol. 55, Page 5587-5594, Year 2016
掲載日	2016年6月18日 (構造データの登録日)
著者	Holden, J.K. / Lewis, M.C. / Cinelli, M.A. / Abdullatif, Z. / Pensa, A.V. / Silverman, R.B. / Poulos, T.L.
リンク	Biochemistry / PubMed:27607918
手法	X線回折
解像度	1.63 - 2.26 Å
構造データ	PDB-5g65: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 2.03 Å PDB-5g66: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 4-methylquinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.76 Å PDB-5g67: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((3-Fluorophenethylamino)methyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.97 Å PDB-5g68: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(2-(3-(3-Fluorophenyl(propylamino)methyl))quinolin-2- amine 手法: X-RAY DIFFRACTION / 解像度: 1.63 Å PDB-5g69: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(2-(3-Fluorobenzylamino)ethyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 2.016 Å PDB-5g6a: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((3-Fluorophenethylamino)ethyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.92 Å PDB-5g6b: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with two molecules of 7-((3-Fluorophenethylamino)ethyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.801 Å PDB-5g6c: Structure of Bacillus subtilis Nitric Oxide Synthase I218V in complex with 7-((3-Fluorophenethylamino)ethyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 2.13 Å PDB-5g6d: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(((3-(Dimethylamino)benzyl)amino)methyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.821 Å PDB-5g6e: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(((3-(Pyridin-3-yl)propyl)amino)methyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 2.111 Å PDB-5g6f: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(((3-((Dimethylamino)methyl)phenyl)amino)methyl) quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 2.26 Å PDB-5g6g: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((2-((Methylamino)methyl)phenoxy)methyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.981 Å PDB-5g6h: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((3-(Methylamino)methyl)phenoxy)methyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.911 Å PDB-5g6i: Structure of Bacillus subtilis Nitric Oxide Synthase I218V in complex with 7-((3-(Methylamino)methyl)phenoxy)methyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.981 Å PDB-5g6j: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((3-(2-(Methylamino)ethyl)phenoxy)methyl)quinolin-2- amine 手法: X-RAY DIFFRACTION / 解像度: 1.88 Å PDB-5g6k: Structure of Bacillus subtilis Nitric Oxide Synthase I218V in complex with 7-((3-(2-(Methylamino)ethyl)phenoxy)methyl)quinolin-2- amine 手法: X-RAY DIFFRACTION / 解像度: 1.951 Å PDB-5g6l: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((4-Chloro-3-((methylamino)methyl)phenoxy)methyl) quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 2.034 Å PDB-5g6m: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((3-Aminomethyl)phenoxy)methyl)quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 1.77 Å PDB-5g6n: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((4-(Dimethylamino)methyl)phenoxy)methyl)quinolin-2- amine 手法: X-RAY DIFFRACTION / 解像度: 1.91 Å PDB-5g6o: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with two molecules of 7-((4-(Dimethylamino)methyl)phenoxy)methyl)quinolin- 2- amine 手法: X-RAY DIFFRACTION / 解像度: 1.719 Å PDB-5g6p: Structure of Bacillus subtilis Nitric Oxide Synthase I218V in complex with 7-((4-(Dimethylamino)methyl)phenoxy)methyl)quinolin-2- amine 手法: X-RAY DIFFRACTION / 解像度: 2.18 Å PDB-5g6q: Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-(((5-((Methylamino)methyl)pyridin-3-yl)oxy)methyl) quinolin-2-amine 手法: X-RAY DIFFRACTION / 解像度: 2.03 Å
化合物	ChemComp-HEM: PROTOPORPHYRIN IX CONTAINING FE ChemComp-CL: Unknown entry / クロリド ChemComp-2AQ: QUINOLIN-2-AMINE / 2-アミノキノリン ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-PEG: DI(HYDROXYETHYL)ETHER / ジエチレングリコ-ル ChemComp-HOH: WATER ChemComp-M5K: 4-METHYLQUINOLIN-2-AMINE / 4-メチルキノリン-2-アミン ChemComp-H4B: 5,6,7,8-TETRAHYDROBIOPTERIN / 6R-テトラヒドロビオプテリン / 神経伝達物質YM ChemComp-M87: 7-[[2-(3-fluorophenyl)ethylamino]methyl]quinolin-2-amine ChemComp-POL: N-PROPANOL / プロパノ-ル ChemComp-ML6: 7-({[3-(3-fluorophenyl)propyl]amino}methyl)quinolin-2-amine ChemComp-BTB: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / ビストリス / pH緩衝剤YM ChemComp-M7K: 7-{2-[(3-fluorobenzyl)amino]ethyl}quinolin-2-amine ChemComp-M48: 7-[2-[2-(3-fluorophenyl)ethylamino]ethyl]quinolin-2-amine / 7-[2-[(3-フルオロフェネチル)アミノ]エチル]キノリン-2-アミン ChemComp-JHT: 7-[[[3-(dimethylamino)phenyl]methylamino]methyl]quinolin-2-amine ChemComp-XH8: 7-(((3-(PYRIDIN-3-YL)PROPYL)AMINO)METHYL)QUINOLIN-2- ChemComp-2SN: 7-[[[3-[(dimethylamino)methyl]phenyl]amino]methyl]quinolin-2-amine ChemComp-H8B: 7-[[2-(methylaminomethyl)phenoxy]methyl]quinolin-2-amine ChemComp-M85: 7-[[3-(methylaminomethyl)phenoxy]methyl]quinolin-2-amine ChemComp-M94: 7-[[3-[2-(methylamino)ethyl]phenoxy]methyl]quinolin-2-amine ChemComp-XEB: 7-[[4-chloranyl-3-(methylaminomethyl)phenoxy]methyl]quinolin-2-amine ChemComp-9M9: 7-[[3-(aminomethyl)phenoxy]methyl]quinolin-2-amine ChemComp-8VJ: 7-[[4-[(dimethylamino)methyl]phenoxy]methyl]quinolin-2-amine ChemComp-TUE: 7-[[5-[(methylideneamino)methyl]pyridin-3-yl]oxymethyl]quinolin-2-amine
由来	bacillus subtilis (枯草菌)
キーワード	OXIDOREDUCTASE / NITRIC OXIDE SYNTHASE / INHIBITOR