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-Structure paper
タイトル | RNA polymerase I-Rrn3 complex at 4.8 Å resolution. |
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ジャーナル・号・ページ | Nat Commun, Vol. 7, Page 12129, Year 2016 |
掲載日 | 2016年7月15日 |
![]() | Christoph Engel / Jürgen Plitzko / Patrick Cramer / ![]() |
PubMed 要旨 | Transcription of ribosomal DNA by RNA polymerase I (Pol I) requires the initiation factor Rrn3. Here we report the cryo-EM structure of the Pol I-Rrn3 complex at 4.8 Å resolution. The structure ...Transcription of ribosomal DNA by RNA polymerase I (Pol I) requires the initiation factor Rrn3. Here we report the cryo-EM structure of the Pol I-Rrn3 complex at 4.8 Å resolution. The structure reveals how Rrn3 binding converts an inactive Pol I dimer into an initiation-competent monomeric complex and provides insights into the mechanisms of Pol I-specific initiation and regulation. |
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手法 | EM (単粒子) |
解像度 | 4.8 Å |
構造データ | |
化合物 | ![]() ChemComp-ZN: |
由来 |
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![]() | RNA POLYMERASE / TRANSCIPTION |