PDB-4zn7: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with Diethylstilbestrol 手法: X-RAY DIFFRACTION / 解像度: 1.934 Å
PDB-4znh: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 2-Fluoro-substituted OBHS derivative 手法: X-RAY DIFFRACTION / 解像度: 1.933 Å
PDB-4zns: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 3-Fluoro-substituted OBHS derivative 手法: X-RAY DIFFRACTION / 解像度: 1.86 Å
PDB-4znt: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 3-Bromo-substituted OBHS derivative 手法: X-RAY DIFFRACTION / 解像度: 1.903 Å
PDB-4znu: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 2-Methyl-substituted OBHS derivative 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å
PDB-4znv: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 2-Methoxy-substituted OBHS derivative 手法: X-RAY DIFFRACTION / 解像度: 1.771 Å
PDB-4znw: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 4-Bromo-substituted OBHS derivative 手法: X-RAY DIFFRACTION / 解像度: 2.31 Å
PDB-5di7: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with an methyl-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-(4-hydroxy-2-methylphenyl)-7a-methyloctahydro-1H-inden-1-ol 手法: X-RAY DIFFRACTION / 解像度: 2.241 Å
PDB-5did: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a difluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-(2,3-difluoro-4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol 手法: X-RAY DIFFRACTION / 解像度: 2.24 Å
PDB-5die: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoro-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-7a-methyl-5-(2,3,5-trifluoro-4-hydroxyphenyl)octahydro-1H-inden-1-ol 手法: X-RAY DIFFRACTION / 解像度: 2.24 Å
PDB-5dig: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoromethyl-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol 手法: X-RAY DIFFRACTION / 解像度: 2.24 Å
PDB-5dk9: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a phenylamino-substituted ethyl triaryl-ethylene derivative 4,4'-{2-[3-(phenylamino)phenyl]but-1-ene-1,1-diyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.28 Å
PDB-5dkb: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 3-methylphenylamino-substituted ethyl triaryl-ethylene derivative 4,4'-(2-{3-[(3-methylphenyl)amino]phenyl}but-1-ene-1,1-diyl)diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å
PDB-5dke: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 3-naphthyl-substituted, methyl, cis-diaryl-ethylene compound 4,4'-[2-(naphthalen-2-yl)prop-1-ene-1,1-diyl]diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å
PDB-5dkg: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a t-butyl-substituted, methyl, triaryl-ethylene derivative 4,4'-[2-(4-tert-butylphenyl)prop-1-ene-1,1-diyl]diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å
PDB-5dks: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 2-naphthylamino-substituted, ethyl, triaryl-ethylene derivative 4,4'-{2-[3-(naphthalen-1-ylamino)phenyl]but-1-ene-1,1-diyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å
PDB-5dl4: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a phenylamino-substituted, methyl, triaryl-ethylene derivative 4,4'-{2-[3-(phenylamino)phenyl]prop-1-ene-1,1-diyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å
PDB-5dlr: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a triaryl-ethylene compound 4,4'-(2-phenylethene-1,1-diyl)diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.26 Å
PDB-5dmc: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a nitrile-substituted triaryl-ethylene derivative 3,3-bis(4-hydroxyphenyl)-2-phenylprop-2-enenitrile 手法: X-RAY DIFFRACTION / 解像度: 2.403 Å
PDB-5dmf: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 4-fluorophenylamino-substituted, methyl triaryl-ethylene derivative 4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}prop-1-ene-1,1-diyl)diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å
PDB-5dp0: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a 4-fluorophenylamino-substituted triaryl-ethylene derivative 4,4'-(2-{3-[(4-fluorophenyl)amino]phenyl}ethene-1,1-diyl)diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.382 Å
PDB-5drj: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a dichloro-substituted, 3-methyl 2,5-diarylthiophene-core ligand 4,4'-(3-methylthiene-2,5-diyl)bis(3-chlorophenol) 手法: X-RAY DIFFRACTION / 解像度: 2.07 Å
PDB-5drm: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a dichloro-substituted, 2,5-diarylthiophene-core ligand 4,4'-thiene-2,5-diylbis(3-chlorophenol) 手法: X-RAY DIFFRACTION / 解像度: 2.241 Å
PDB-5dtv: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a dimethyl-substituted, 3,4-diarylthiophene dioxide core ligand 手法: X-RAY DIFFRACTION / 解像度: 2.295 Å
PDB-5du5: Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a dichloro-substituted, 3,4-diarylthiophene dioxide core ligand 手法: X-RAY DIFFRACTION / 解像度: 2.195 Å
PDB-5due: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a para-Hydroxyl-substituted, Sulfoxide-bridged Oxabicyclic Heptene Sulfonate (SOBHS)-2 Analog 4-hydroxyphenyl (1S,2S,4S,5S,6R,7S)-5,6-bis(4-hydroxy-2-methylphenyl)-7-thiabicyclo[2.2.1]heptane-2-sulfonate 7-oxide 手法: X-RAY DIFFRACTION / 解像度: 2.09 Å
PDB-5dug: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Sulfoxide-bridged Oxabicyclic Heptene Sulfonate (SOBHS)-2 analog phenyl (1S,2S,4S,7S)-5,6-bis(4-hydroxy-2-methylphenyl)-7-thiabicyclo[2.2.1]hept-5-ene-2-sulfonate 7-oxide 手法: X-RAY DIFFRACTION / 解像度: 2.252 Å
PDB-5duh: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Sulfoxide-bridged Oxabicyclic Heptene Sulfonate (SOBHS)-3 analog phenyl (1S,2S,4S,7S)-5,6-bis(4-hydroxy-3-methylphenyl)-7-thiabicyclo[2.2.1]hept-5-ene-2-sulfonate 7-oxide 手法: X-RAY DIFFRACTION / 解像度: 2.24 Å
PDB-5dvs: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a 2-Methyl-substituted Triaryl-imine 4,4'-[(2-methylphenyl)carbonimidoyl]diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.28 Å
PDB-5dvv: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Triaryl-imine analog 4,4'-(phenylcarbonimidoyl)diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.505 Å
PDB-5dwe: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a 2-Chloro-substituted Triaryl-imine analog 4,4'-[(2-chlorophenyl)carbonimidoyl]diphenol 手法: X-RAY DIFFRACTION / 解像度: 1.92 Å
PDB-5dwg: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Triaryl-substituted Imine Analog, 4-{(E)-(4-hydroxyphenyl)[(2-methylphenyl)imino]methyl}benzene-1,3-diol 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å
PDB-5dwi: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Resorcinyl 2-Chloro-substituted Diaryl-imine analog 4-[(E)-[(2-chlorophenyl)imino](4-hydroxyphenyl)methyl]benzene-1,3-diol 手法: X-RAY DIFFRACTION / 解像度: 2.43 Å
PDB-5dwj: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with a Resorcinyl 4-Fluoro-substituted Diaryl-imine analog 4-[(E)-[(4-fluorophenyl)imino](4-hydroxyphenyl)methyl]benzene-1,3-diol 手法: X-RAY DIFFRACTION / 解像度: 2.001 Å
PDB-5dxk: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(9s)-bicyclo[3.3.1]non-9-ylmethanediyl]diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.226 Å
PDB-5dxm: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 3-[(E)-(1s,5s)-bicyclo[3.3.1]non-9-ylidene(4-hydroxyphenyl)methyl]phenol 手法: X-RAY DIFFRACTION / 解像度: 2.37 Å
PDB-5dxp: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4-[(E)-(1s,5s)-bicyclo[3.3.1]non-9-ylidene(phenyl)methyl]phenol 手法: X-RAY DIFFRACTION / 解像度: 2.201 Å
PDB-5dxq: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(1s,5s)-bicyclo[3.3.1]non-9-ylidenemethanediyl]diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å
PDB-5dxr: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3R)-3-methylcyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.28 Å
PDB-5dy8: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-ethylcyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.031 Å
PDB-5dyb: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-(3,4-dihydronaphthalen-2(1H)-ylidenemethanediyl)diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.27 Å
PDB-5dyd: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-(methylsulfanyl)cyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.485 Å
PDB-5dz0: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(4-methylcyclohexylidene)methanediyl]diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.24 Å
PDB-5dz1: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(4-ethylcyclohexylidene)methanediyl]diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å
PDB-5dz3: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[4-(fluoromethyl)cyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å
PDB-5dzh: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[4-(2-hydroxyethyl)cyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.11 Å
PDB-5dzi: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-(2-hydroxyethyl)cyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å
PDB-5e0w: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-(4-hydroxyphenyl)cyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2 Å
PDB-5e0x: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3S)-3-(4-methoxyphenyl)cyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.014 Å
PDB-5e14: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3R)-3-phenylcyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.22 Å
PDB-5e15: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[4-(2-hydroxyethyl)cyclohexylidene]methanediyl}diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å
PDB-5e19: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative methyl {4-[bis(4-hydroxyphenyl)methylidene]cyclohexyl}acetate 手法: X-RAY DIFFRACTION / 解像度: 2.24 Å
PDB-5e1c: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative dimethyl {(1S)-3-[bis(4-hydroxyphenyl)methylidene]cyclohexyl}propanedioate 手法: X-RAY DIFFRACTION / 解像度: 1.98 Å
PDB-5egv: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex the 3,4-diaryl-furan derivative 3-chloranyl-4-[4-(2-chloranyl-4-oxidanyl-phenyl)furan-3-yl]phenol 手法: X-RAY DIFFRACTION / 解像度: 2.863 Å
PDB-5ehj: Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-[(4aR,8aR)-octahydronaphthalen-2(1H)-ylidenemethanediyl]diphenol 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å
PDB-5ei1: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the imidazopyridine derivative 2-(4-hydroxyphenyl)-3-iodanyl-imidazo[1,2-a]pyridin-6-ol 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å
PDB-5eit: Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the imidazopyridine derivative 2-(4-hydroxyphenyl)-3-(trifluoromethyl)imidazo[1,2-a]pyridin-6-ol 手法: X-RAY DIFFRACTION / 解像度: 2.68 Å
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