EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.
ジャーナル・号・ページ	Acs Chem. Biol., Vol. 10, Page 1340-1351, Year 2015
掲載日	2014年12月9日 (構造データの登録日)
著者	Bernard, S.M. / Akey, D.L. / Tripathi, A. / Park, S.R. / Konwerski, J.R. / Anzai, Y. / Li, S. / Kato, F. / Sherman, D.H. / Smith, J.L.
リンク	Acs Chem. Biol. / PubMed:25692963
手法	X線回折
解像度	1.4 - 2.49 Å
構造データ	PDB-4x7u: MycF mycinamicin III 3'-O-methyltransferase in complex with Mg, SAH and mycinamicin III (substrate) 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-4x7v: MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and mycinamicin IV (product) 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-4x7w: MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and mycinamicin VI (MycE substrate) 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-4x7x: MycF mycinamicin III 3'-O-methyltransferase (E35Q, E139A variant) in complex with Mg, SAH and macrocin 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-4x7y: MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg and SAH 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-4x7z: MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg, SAH and mycinamicin III (substrate) 手法: X-RAY DIFFRACTION / 解像度: 1.44 Å PDB-4x81: MycF mycinamicin III 3'-O-methyltransferase (E35Q, M56A, E139A variant) in complex with Mg, SAH and mycinamicin VI (MycE substrate) 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å PDB-4xvy: MycF mycinamicin III 3'-O-methyltransferase in complex with SAH 手法: X-RAY DIFFRACTION / 解像度: 2.42 Å PDB-4xvz: MycF mycinamicin III 3'-O-methyltransferase in complex with Mg 手法: X-RAY DIFFRACTION / 解像度: 2.49 Å
化合物	ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-SAH: S-ADENOSYL-L-HOMOCYSTEINE / S-アデノシルホモシステイン ChemComp-ZM3: MYCINAMICIN III ChemComp-HOH: WATER ChemComp-MIV: MYCINAMICIN IV ChemComp-MVI: Mycinamicin VI ChemComp-3ZP: 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-[(2R,3R,4R,5S,6R)-4-(dimethylamino)-5-[(2S,4R,5S,6S)-4,6-dimethyl-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-methyl-3-oxidanyl-oxan-2-yl]oxy-16-ethyl-15-[[(2R,3R,4R,5S,6R)-3-methoxy-6-methyl-4,5-bis(oxidanyl)oxan-2-yl]oxymethyl]-5,9,13-trimethyl-4-oxidanyl-2,10-bis(oxidanylidene)-1-oxacyclohexadeca-11,13-dien-7-yl]ethanal / 抗生剤YM ChemComp-DMS: DIMETHYL SULFOXIDE / 2-チアプロパン2-オキシド / DMSO, 沈殿剤YM ChemComp-CL: Unknown entry / クロリド
由来	micromonospora griseorubida (バクテリア)
キーワード	Transferase/Antibiotic / macrolide / methyltransferase / antibiotic / natural product / Transferase-Antibiotic complex / Transferase/Antiobiotic / Transferase-Antiobiotic complex / TRANSFERASE