タイトル | Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism. |
---|
ジャーナル・号・ページ | Nat. Chem. Biol., Vol. 11, Page 847-854, Year 2015 |
---|
掲載日 | 2014年10月7日 (構造データの登録日) |
---|
著者 | Yu, H. / Takeuchi, M. / LeBarron, J. / Kantharia, J. / London, E. / Bakker, H. / Haltiwanger, R.S. / Li, H. / Takeuchi, H. |
---|
リンク | Nat. Chem. Biol. / PubMed:26414444 |
---|
手法 | X線回折 |
---|
解像度 | 1.62 - 3.03 Å |
---|
構造データ | PDB-4wlg: crystal structure of mouse Xyloside xylosyltransferase 1, apo form 手法: X-RAY DIFFRACTION / 解像度: 3 Å PDB-4wlm: Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese 手法: X-RAY DIFFRACTION / 解像度: 3 Å PDB-4wlz: Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese and UDP 手法: X-RAY DIFFRACTION / 解像度: 3.03 Å PDB-4wm0: Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with acceptor ligand 手法: X-RAY DIFFRACTION / 解像度: 2.37 Å PDB-4wma: Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese,acceptor ligand and UDP-Glucose 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-4wmb: crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, acceptor ligand and UDP 手法: X-RAY DIFFRACTION / 解像度: 2.05 Å PDB-4wmi: Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, product ligand and UDP (Product complex I) 手法: X-RAY DIFFRACTION / 解像度: 1.87 Å PDB-4wmk: Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, product ligand and UDP (Product complex II) 手法: X-RAY DIFFRACTION / 解像度: 2.08 Å PDB-4wn2: Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, product ligand and UDP (Product complex III) 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å |
---|
化合物 | |
---|
由来 | ![](img/tx_mammal.gif) mus musculus (ハツカネズミ) homo sapiens (ヒト)
|
---|
キーワード | TRANSFERASE / glycosyltransferase / apo from / manganese binding / transferase/protein binding / transferase-protein binding complex / transferase/transferase inhibitor / transferase-transferase inhibitor complex |
---|