タイトル | Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA. |
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ジャーナル・号・ページ | Nucleic Acids Res., Vol. 40, Page 9917-9926, Year 2012 |
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掲載日 | 2012年3月21日 (構造データの登録日) |
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著者 | Morera, S. / Grin, I. / Vigouroux, A. / Couve, S. / Henriot, V. / Saparbaev, M. / Ishchenko, A.A. |
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リンク | Nucleic Acids Res. / PubMed:22848106 |
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手法 | X線回折 |
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解像度 | 1.79 - 3 Å |
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構造データ | PDB-4e9e: Structure of the glycosylase domain of MBD4 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-4e9f: Structure of the glycosylase domain of MBD4 bound to AP site containing DNA 手法: X-RAY DIFFRACTION / 解像度: 1.79 Å PDB-4e9g: structure of the glycosylase domain of MBD4 bound to thymine containing DNA 手法: X-RAY DIFFRACTION / 解像度: 2.35 Å PDB-4e9h: structure of glycosylase domain of MBD4 bound to 5hmU containing DNA 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-4ea4: Structure of the glycosylase domain of MBD4 bound to 5hmU-containing DNA 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å PDB-4ea5: Structure of the glycoslyase domain of MBD4 bound to a 5hmU containing DNA 手法: X-RAY DIFFRACTION / 解像度: 2.14 Å |
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化合物 | |
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由来 | homo sapiens (ヒト)- synthetic (人工物)
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キーワード | HYDROLASE / HhH DNA glycosylase superfamily / HYDROLASE/DNA / HhH DNA glycosylase family / HYDROLASE-DNA complex |
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