EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the S. Aureus Fabi Enzyme-Product Complex.
ジャーナル・号・ページ	Biochemistry, Vol. 52, Page 4217-, Year 2013
掲載日	2013年5月15日 (構造データの登録日)
著者	Chang, A. / Schiebel, J. / Yu, W. / Bommineni, G.R. / Pan, P. / Baxter, M.V. / Khanna, A. / Sotriffer, C.A. / Kisker, C.F. / Tonge, P.J.
リンク	Biochemistry / PubMed:23697754
手法	X線回折
解像度	2.15 - 2.5 Å
構造データ	PDB-4bnf: Crystal structure of S. aureus FabI in complex with NADP and 2- phenoxy-5-propylphenol 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-4bng: Crystal structure of S. aureus FabI in complex with NADP and 5-pentyl- 2-phenoxyphenol 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-4bnh: Crystal structure of S. aureus FabI in complex with NADP and 5-hexyl- 2-phenoxyphenol 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-4bni: Crystal structure of S. aureus FabI in complex with NADP and 2-(2- aminophenoxy)-5-hexylphenol 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-4bnj: Crystal structure of S. aureus FabI in complex with NADP and 5-methyl- 2-phenoxyphenol 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-4bnk: Crystal structure of S. aureus FabI in complex with NADP and 5-fluoro- 2-phenoxyphenol 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-4bnl: Crystal structure of S. aureus FabI in complex with NADP and 2- phenoxy-5-(2-propenyl)phenol 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-4bnm: Crystal structure of S. aureus FabI in complex with NADP and 5-hexyl- 2-(2-methylphenoxy)phenol 手法: X-RAY DIFFRACTION / 解像度: 2.35 Å PDB-4bnn: Crystal structure of S. aureus FabI in complex with NADP and 2-(2- cyanophenoxy)-5-hexylphenol 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å
化合物	ChemComp-GLU: GLUTAMIC ACID ChemComp-NAP: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE ChemComp-PV4: 2-phenoxy-5-propyl-phenol ChemComp-HOH: WATER ChemComp-5PP: 5-PENTYL-2-PHENOXYPHENOL ChemComp-6PN: 5-hexyl-2-phenoxyphenol ChemComp-P1F: 2-(2-azanylphenoxy)-5-hexyl-phenol ChemComp-MJ5: 5-methyl-2-phenoxyphenol ChemComp-FPL: 5-fluoro-2-phenoxyphenol ChemComp-CL: Unknown entry ChemComp-W1G: 2-PHENOXY-5-(2-PROPENYL)PHENOL ChemComp-TCU: 5-HEXYL-2-(2-METHYLPHENOXY)PHENOL ChemComp-JUS: 2-(2-CYANOPHENOXY)-5-HEXYLPHENOL
由来	staphylococcus aureus subsp. aureus (黄色ブドウ球菌) staphylococcus aureus (黄色ブドウ球菌)
キーワード	OXIDOREDUCTASE / SHORT-CHAIN DEHYDROGENASE/REDUCTASE SUPERFAMILY / FATTY ACID BIOSYNTHESIS / LIPID SYNTHESIS / SAFABI