EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors.
ジャーナル・号・ページ	J. Mol. Biol., Vol. 413, Page 667-683, Year 2011
掲載日	2008年5月1日 (構造データの登録日)
著者	Unno, M. / Shinohara, M. / Takayama, K. / Tanaka, H. / Teruya, K. / Doh-Ura, K. / Sakai, R. / Sasaki, M. / Ikeda-Saito, M.
リンク	J. Mol. Biol. / PubMed:21893069
手法	X線回折
解像度	1.5 - 2 Å
構造データ	PDB-2zns: Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with glutamate 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-2znt: Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with a novel selective agonist, dysiherbaine 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-2znu: Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with a novel selective agonist, neodysiherbaine A 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-3fuz: Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with L-glutamate in space group P1 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-3fv1: Crystal Structure of the human glutamate receptor, GluR5, ligand-binding core in complex with dysiherbaine in space group P1 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-3fv2: Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with neodysiherbaine A in space group P1 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-3fvg: Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with MSVIII-19 in space group P1 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-3fvk: Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with 8-deoxy-neodysiherbaine A in space group P1 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-3fvn: Crystal structure of the human glutamate receptor, GluR5, ligand-binding core in complex with 9-deoxy-neodysiherbaine A in space group P1 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-3qxm: Crystal Structure of Human GluK2 Ligand-Binding Core in Complex with Novel Marine-Derived Toxins, Neodysiherbaine A 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å
化合物	ChemComp-GLU: GLUTAMIC ACID / グルタミン酸 ChemComp-HOH: WATER ChemComp-DYH: (2R,3aR,6S,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6-hydroxy-7-(methylamino)hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid / ジシヘルバイン ChemComp-BME: BETA-MERCAPTOETHANOL / 2-メルカプトエタノ-ル ChemComp-NDZ: (2R,3aR,6R,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6,7-dihydroxyhexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid / ネオジシヘルバインA ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-MS8: (2R,3aR,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid / MSVIII-19 ChemComp-8DX: (2R,3aR,6S,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-6-hydroxy-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid / 8-デオキシネオジシヘルバインA ChemComp-9DX: (2R,3aR,7R,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-7-hydroxy-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid / 9-デオキシネオジシヘルバインA
由来	homo sapiens (ヒト)
キーワード	MEMBRANE PROTEIN / GluR5-S1S2 / kainate receptor / ligand-binding core / Alternative splicing / Cell junction / Glycoprotein / Ion transport / Ionic channel / Membrane / Phosphoprotein / Polymorphism / Postsynaptic cell membrane / RNA editing / Synapse / Transmembrane / Transport / GluR5 / amino acid / agonist / dysiherbaine / neodysiherbaine A / human glutamate receptor / Natural compound / glutamate receptor / ligand / dysiherbaine analogue / ligand-binding domain / 8-deoxy-neodysiherbaine / 9-deoxy-neodysiherbaine / two domains / ligand-binding