EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
ジャーナル・号・ページ	Angew. Chem. Int. Ed. Engl., Vol. 49, Page 337-340, Year 2010
掲載日	2008年12月19日 (構造データの登録日)
著者	Wu, H.J. / Ho, C.W. / Ko, T.P. / Popat, S.D. / Lin, C.H. / Wang, A.H.
リンク	Angew. Chem. Int. Ed. Engl. / PubMed:19967696
手法	X線回折
解像度	2.15 - 2.65 Å
構造データ	PDB-2zwz: alpha-L-fucosidase complexed with inhibitor, Core1 手法: X-RAY DIFFRACTION / 解像度: 2.36 Å PDB-2zx5: alpha-L-fucosidase complexed with inhibitor, F10 手法: X-RAY DIFFRACTION / 解像度: 2.65 Å PDB-2zx6: alpha-L-fucosidase complexed with inhibitor, F10-1C 手法: X-RAY DIFFRACTION / 解像度: 2.42 Å PDB-2zx7: alpha-L-fucosidase complexed with inhibitor, F10-2C 手法: X-RAY DIFFRACTION / 解像度: 2.48 Å PDB-2zx8: alpha-L-fucosidase complexed with inhibitor, F10-2C-O 手法: X-RAY DIFFRACTION / 解像度: 2.33 Å PDB-2zx9: alpha-L-fucosidase complexed with inhibitor, B4 手法: X-RAY DIFFRACTION / 解像度: 2.62 Å PDB-2zxa: alpha-L-fucosidase complexed with inhibitor, FNJ-acetyl 手法: X-RAY DIFFRACTION / 解像度: 2.57 Å PDB-2zxb: alpha-L-fucosidase complexed with inhibitor, ph-6FNJ 手法: X-RAY DIFFRACTION / 解像度: 2.61 Å PDB-2zxd: alpha-L-fucosidase complexed with inhibitor, iso-6FNJ 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å
化合物	ChemComp-ZWZ: (2R,3R,4R,5R,6S)-2-(aminomethyl)-6-methylpiperidine-3,4,5-triol / (2R)-2α-(アミノメチル)-6α-メチルピペリジン-3β,4α,5α-トリオ-ル ChemComp-HOH: WATER ChemComp-ZX5: 3-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}propanamide / N-[(3β,4α,5α-トリヒドロキシ-6α-メチルピペリジン-2α-イル)メチル]-3-(1H-インド-ル-3-イ(以下略) ChemComp-ZX6: 2-(1H-indol-3-yl)-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide ChemComp-ZX7: N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1H-indole-2-carboxamide ChemComp-ZX8: N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1-benzofuran-2-carboxamide ChemComp-ZX9: (2S)-2-cyclopentyl-2-phenyl-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}ethanamide ChemComp-ZXA: N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}acetamide / N-[[(2R)-3β,4α,5α-トリヒドロキシ-6α-メチルピペリジン-2α-イル]メチル]アセトアミド ChemComp-ZXB: (2S,3R,4S,5R)-2-benzylpiperidine-3,4,5-triol ChemComp-ZXD: (2S,3R,4S,5R)-2-(1-methylethyl)piperidine-3,4,5-triol / 6,6-ジメチル-1,5-イミノ-1,5,6-トリデオキシ-L-ガラクチト-ル
由来	thermotoga maritima (バクテリア)
キーワード	HYDROLASE / Tim Barrel