タイトル | Crystallographic Analysis of the Reaction Cycle of 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family |
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ジャーナル・号・ページ | J. Mol. Biol., Vol. 425, Page 4307-, Year 2013 |
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掲載日 | 2012年10月29日 (構造データの登録日) |
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著者 | Myllykoski, M. / Raasakka, A. / Lehtimaki, M. / Han, H. / Kursula, I. / Kursula, P. |
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リンク | J. Mol. Biol. / PubMed:23831225 |
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手法 | X線回折 |
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解像度 | 1.894 - 2.45 Å |
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構造データ | PDB-2yoz: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-AMPS 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-2yp0: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, crystallized with 2'-AMPS 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-2ypc: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S, crystallized with 2',3-(SP)-Cyclic-AMPS 手法: X-RAY DIFFRACTION / 解像度: 1.894 Å PDB-2ype: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H309S, crystallized with 2',3'- cyclic AMP 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-2yph: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S, crystallized with 2',3-(RP)- cyclic-AMPS 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-2yq9: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, crystallized with 2'-AMP 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-3zbr: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation H230S, crystallized with NADP 手法: X-RAY DIFFRACTION / 解像度: 2.304 Å PDB-3zbs: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, crystallized with 2'-AMPS 手法: X-RAY DIFFRACTION / 解像度: 2.45 Å PDB-3zbz: Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation V321A, crystallized with 2'-AMPS 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å |
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化合物 | ChemComp-QQX: [(3aR,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2-oxidanyl-2-sulfanylidene-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-6-yl]methanol
ChemComp-QQY: [(3aR,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2-oxidanylidene-2-sulfanyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-6-yl]methanol
ChemComp-NAP: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
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由来 | - mus musculus (ハツカネズミ)
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キーワード | HYDROLASE / MYELIN / NERVOUS SYSTEM |
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