EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structure-Guided Design of Cell Wall Biosynthesis Inhibitors that Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa).
ジャーナル・号・ページ	Acs Chem. Biol., Vol. 6, Page 943-, Year 2011
掲載日	2010年12月15日 (構造データの登録日)
著者	Contreras-Martel, C. / Amoroso, A. / Woon, E.C. / Zervosen, A. / Inglis, S. / Martins, A. / Verlaine, O. / Rydzik, A. / Job, V. / Luxen, A. ...Contreras-Martel, C. / Amoroso, A. / Woon, E.C. / Zervosen, A. / Inglis, S. / Martins, A. / Verlaine, O. / Rydzik, A. / Job, V. / Luxen, A. / Joris, B. / Schofield, C.J. / Dessen, A.
リンク	Acs Chem. Biol. / PubMed:21732689
手法	X線回折
解像度	1.62 - 2.15 Å
構造データ	PDB-2y2g: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (A01) 手法: X-RAY DIFFRACTION / 解像度: 2.05 Å PDB-2y2h: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA2) 手法: X-RAY DIFFRACTION / 解像度: 1.96 Å PDB-2y2i: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA3) 手法: X-RAY DIFFRACTION / 解像度: 1.78 Å PDB-2y2j: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA4) 手法: X-RAY DIFFRACTION / 解像度: 2.06 Å PDB-2y2k: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (ZA5) 手法: X-RAY DIFFRACTION / 解像度: 2.09 Å PDB-2y2l: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (E06) 手法: X-RAY DIFFRACTION / 解像度: 2.07 Å PDB-2y2m: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (E08) 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-2y2n: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (E07) 手法: X-RAY DIFFRACTION / 解像度: 2.07 Å PDB-2y2o: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (EO9) 手法: X-RAY DIFFRACTION / 解像度: 1.88 Å PDB-2y2p: Penicillin-binding protein 1b (pbp-1b) in complex with an alkyl boronate (z10) 手法: X-RAY DIFFRACTION / 解像度: 1.62 Å PDB-2y2q: PENICILLIN-BINDING PROTEIN 1B (PBP-1B) IN COMPLEX WITH AN ALKYL BORONATE (Z06) 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å
化合物	ChemComp-A01: [(2,6-DIMETHOXYPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-CL: Unknown entry / クロリド ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-HOH: WATER ChemComp-ZA2: [(2-CHLOROPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON ChemComp-ZA3: TRIHYDROXY-[[(2-NITROPHENYL)CARBONYLAMINO]METHYL]BORON ChemComp-ZA4: [(2-FLUOROPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON ChemComp-ZA5: [(2,6-DIFLUOROPHENYL)CARBONYLAMINO]METHYL-TRIHYDROXY-BORON ChemComp-E06: [(1R)-1-[(2,6-difluorophenyl)carbonylamino]ethyl]-trihydroxy-boron ChemComp-E08: TRIHYDROXY-[(1S)-1-[(2-PROPAN-2-YLPHENYL)CARBONYLAMINO]ETHYL]BORON ChemComp-E07: TRIHYDROXY-[(1S)-1-[[2-(PHENYLMETHYL)PHENYL]CARBONYLAMINO]ETHYL]BORON ChemComp-EO9: [(1S)-1-[(2,6-difluorophenyl)carbonylamino]ethyl]-trihydroxy-boron ChemComp-Z10: [(1S)-1-[(2-fluoro-6-phenyl-phenyl)carbonylamino]ethyl]-trihydroxy-boron ChemComp-Z06: (3-acetamido-5-carboxy-phenyl)-trihydroxy-boron
由来	streptococcus pneumoniae (肺炎レンサ球菌)
キーワード	TRANSFERASE / INFECTION / CELL WALL / PEPTIDOGLYCAN / INHIBITOR