EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	A surface on the androgen receptor that allosterically regulates coactivator binding.
ジャーナル・号・ページ	Proc. Natl. Acad. Sci. Usa, Vol. 104, Page 16074-16079, Year 2007
掲載日	2007年4月13日 (構造データの登録日)
著者	Estebanez-Perpina, E. / Arnold, L.A. / Arnold, A.A. / Nguyen, P. / Rodrigues, E.D. / Mar, E. / Bateman, R. / Pallai, P. / Shokat, K.M. / Baxter, J.D. ...Estebanez-Perpina, E. / Arnold, L.A. / Arnold, A.A. / Nguyen, P. / Rodrigues, E.D. / Mar, E. / Bateman, R. / Pallai, P. / Shokat, K.M. / Baxter, J.D. / Guy, R.K. / Webb, P. / Fletterick, R.J.
リンク	Proc. Natl. Acad. Sci. Usa / PubMed:17911242
手法	X線回折
解像度	1.76 - 2.58 Å
構造データ	PDB-2pio: Androgen receptor LBD with small molecule 手法: X-RAY DIFFRACTION / 解像度: 2.03 Å PDB-2pip: Androgen receptor LBD with small molecule 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-2piq: androgen receptor LBD with small molecule 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-2pir: Androgen receptor LBD with small molecule 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-2pit: Androgen receptor LBD with small molecule 手法: X-RAY DIFFRACTION / 解像度: 1.76 Å PDB-2piu: Androgen receptor LBD with small molecule 手法: X-RAY DIFFRACTION / 解像度: 2.12 Å PDB-2piv: Androgen receptor with small molecule 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-2piw: Androgen receptor with small molecule 手法: X-RAY DIFFRACTION / 解像度: 2.58 Å PDB-2pix: AR LBD with small molecule 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-2pkl: Androgen receptor LBD with small molecule 手法: X-RAY DIFFRACTION / 解像度: 2.49 Å PDB-2qpy: AR LBD with small molecule 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å
化合物	ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-DHT: 5-ALPHA-DIHYDROTESTOSTERONE / ジヒドロテストステロン / ホルモンYM ChemComp-2MI: 2-METHYL-1H-INDOLE / 2-メチル-1H-インド-ル ChemComp-HOH: WATER ChemComp-ICO: 1H-INDOLE-3-CARBOXYLIC ACID / 1H-インド-ル-3-カルボン酸 ChemComp-K10: 1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE ChemComp-RB1: 3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL ChemComp-NK: SALICYLALDEHYDE / サリチルアルデヒド ChemComp-4HY: [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID / 3,3′,5-トリヨ-ドチロ酢酸 / ホルモンYM ChemComp-T3: 3,5,3'TRIIODOTHYRONINE / トリヨ-ドチロニン / ホルモンYM ChemComp-FLF: 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID / フルフェナム酸 / 抗炎症剤, 阻害剤YM
由来	homo sapiens (ヒト) mus musculus (ハツカネズミ) synthetic construct (人工物)
キーワード	HORMONE RECEPTOR / androgen receptor ligand binding domain / inhibitors coactivator binding AF-2 pocket / androgen receptor / coactivators / AF-2 pocket / inhibitors / inhibitors coactivator binding AF-2 / androgen receptor coactivator binding inhibitors AF-2 pocket / androgen receptor coactivator binding inhibitors AF-2 / androgen receptor inhibitors coactivator binding AF-2 / androgen receptor inhibitor coactivator binding / androgen receptor inhibitors coactivator binding / AR LBD ihnibitors coactivator binding / androgen receptor coactivators AF2 inhibitors / DNA BINDING PROTEIN / androgen receptor DHT coactivator / DNA-binding / Lipid-binding / Metal-binding / Nucleus / Steroid-binding / Transcription / Transcription regulation / Ubl conjugation / Zinc / Zinc-finger