タイトル Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein helping to drive the genesis of Omicron variants ジャーナル・号・ページ To Be Published 掲載日 2024年5月10日 (構造データの登録日) 著者Yan Q / Gao X / Liu B / Hou R / He P / Ma Y / Zhang Y / Li Z / Chen Q / Wang J ...Yan Q / Gao X / Liu B / Hou R / He P / Ma Y / Zhang Y / Li Z / Chen Q / Wang J / Huang X / Liang H / Zheng H / Yao Y / Chen X / Niu X / He J / Chen L / Zhao J / Xiong X リンクPubMedで検索 手法 EM (単粒子) 解像度 3.16 - 8.45 Å 構造データ EMDB-60099 , PDB-8zhd : SARS-CoV-2 spike trimer (6P) in complex with two R1-26 Fabs手法 : EM (単粒子) / 解像度 : 3.41 Å
EMDB-60100 , PDB-8zhe : SARS-CoV-2 spike trimer (6P) in complex with three R1-26 Fabs手法 : EM (単粒子) / 解像度 : 3.16 Å
EMDB-60101 , PDB-8zhf : SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, head-to-head aggregate 手法 : EM (単粒子) / 解像度 : 5.26 Å
EMDB-60102 , PDB-8zhg : SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, focused refinement of RBD-Fab region 手法 : EM (単粒子) / 解像度 : 3.51 Å
EMDB-60103 , PDB-8zhh : SARS-CoV-2 spike trimer (6P) in complex with two H18 Fabs手法 : EM (単粒子) / 解像度 : 5.55 Å
EMDB-60104 , PDB-8zhi : SARS-CoV-2 spike trimer (6P) in complex with three H18 Fabs手法 : EM (単粒子) / 解像度 : 6.05 Å
EMDB-60105 , PDB-8zhj : SARS-CoV-2 spike trimer (6P) in complex with three H18 Fabs, head-to-head aggregate (C1 symmetry)手法 : EM (単粒子) / 解像度 : 8.45 Å
EMDB-60106 , PDB-8zhk : SARS-CoV-2 spike trimer (6P) in complex with three H18 Fabs, head-to-head aggregate (C3 symmetry)手法 : EM (単粒子) / 解像度 : 6.3 Å
EMDB-60107 , PDB-8zhl : SARS-CoV-2 spike trimer (6P) in complex with two H18 and two R1-32 Fabs手法 : EM (単粒子) / 解像度 : 3.96 Å
EMDB-60108 , PDB-8zhm : SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs手法 : EM (単粒子) / 解像度 : 3.39 Å
EMDB-60109 , PDB-8zhn : SARS-CoV-2 spike trimer (6P) in complex with three H18 and three R1-32 Fabs (one RBD rotated) 手法 : EM (単粒子) / 解像度 : 4.12 Å
EMDB-60110 , PDB-8zho : SARS-CoV-2 S1 in complex with H18 and R1-32 Fab 手法 : EM (単粒子) / 解像度 : 3.54 Å
EMDB-60111 , PDB-8zhp :Dimer of SARS-CoV-2 S1 in complex with H18 and R1-32 Fabs手法 : EM (単粒子) / 解像度 : 3.66 Å
化合物 由来 enterobacteria phage t6 (ファージ)homo sapiens (ヒト)synthetic construct (人工物) severe acute respiratory syndrome coronavirus 2 (ウイルス) キーワード VIRAL PROTEIN/IMMUNE SYSTEM / Spike protein / RBD / Antibody / Fab / Viral protein / VIRAL PROTEIN-IMMUNE SYSTEM complex