EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase
ジャーナル・号・ページ	Chemistry, Vol. 15, Page 6619-6625, Year 2009
掲載日	2008年10月16日 (構造データの登録日)
著者	Heinrich, D. / Diederichsen, U. / Rudolph, M.G.
リンク	Chemistry / PubMed:19472232
手法	X線回折
解像度	1.1 - 1.74 Å
構造データ	PDB-3ewu: D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-acetyl-UMP, covalent adduct 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-3eww: D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-cyano-UMP, covalent adduct 手法: X-RAY DIFFRACTION / 解像度: 1.1 Å PDB-3ewx: K314A mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, degraded to BMP 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-3ewy: K314A mutant of human orotidyl-5'-monophosphate decarboxylase soaked with OMP, decarboxylated to UMP 手法: X-RAY DIFFRACTION / 解像度: 1.1 Å PDB-3ewz: human orotidyl-5'-monophosphate decarboxylase in complex with 5-cyano-UMP 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-3ex1: human orotidyl-5'-monophosphate decarboxylase soaked with 6-cyano-UMP, converted to UMP 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-3ex2: human orotidyl-5'-monophosphate decarboxylase in complex with 6-cyano-UMP 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-3ex3: human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, covalent adduct 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-3ex4: human orotidyl-5'-monophosphate decarboxylase in complex with BMP 手法: X-RAY DIFFRACTION / 解像度: 1.24 Å PDB-3ex6: D312N mutant of human orotidyl-5'-monophosphate decarboxylase in complex with 6-azido-UMP, covalent adduct 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å PDB-3l0k: Human orotidyl-5'-monophosphate decarboxylase in complex with 6-acetyl-UMP 手法: X-RAY DIFFRACTION / 解像度: 1.34 Å PDB-3l0n: Human orotidyl-5'-monophosphate decarboxylase in complex with 6-mercapto-UMP 手法: X-RAY DIFFRACTION / 解像度: 1.74 Å
化合物	ChemComp-GOL: GLYCEROL / グリセロ-ル / グリセリン ChemComp-UEP: 6-ethyluridine 5'-phosphate ChemComp-SO4: SULFATE ION / 硫酸ジアニオン / 硫酸塩 ChemComp-HOH: WATER / 水 ChemComp-U1P: 6-[(E)-iminomethyl]uridine 5'-phosphate ChemComp-BMP: 6-HYDROXYURIDINE-5'-PHOSPHATE / 6-ヒドロキシウリジン5′-りん酸 ChemComp-U5P: URIDINE-5'-MONOPHOSPHATE / UMP / ウリジル酸 ChemComp-CNU: 5-CYANO-URIDINE-5'-MONOPHOSPHATE ChemComp-6CN: 6-cyanouridine 5'-phosphate / 6-シアノウリジン5′-りん酸 ChemComp-CL: Unknown entry / クロリド / 塩化物 ChemComp-6AU: 6-acetyluridine 5'-phosphate ChemComp-S5P: 6-sulfanyluridine-5'-phosphate
由来	homo sapiens (ヒト)
キーワード	LYASE (リアーゼ) / decarboxylation / unusual catalysis / tim barrel (TIMバレル) / Decarboxylase (脱炭酸酵素) / Disease mutation / Glycosyltransferase (グリコシルトランスフェラーゼ) / Multifunctional enzyme / Pyrimidine biosynthesis / Transferase (転移酵素) / Alternative splicing (選択的スプライシング) / Polymorphism