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-Structure paper
Title | Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance. |
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Journal, issue, pages | Immunity, Vol. 57, Page 890-903.e6, Year 2024 |
Publish date | Feb 14, 2024 (structure data deposition date) |
Authors | Ogega, C.O. / Skinner, N.E. / Schoenle, M.V. / Wilcox, X.E. / Frumento, N. / Wright, D.A. / Paul, H.T. / Sinnis-Bourozikas, A. / Clark, K.E. / Figueroa, A. ...Ogega, C.O. / Skinner, N.E. / Schoenle, M.V. / Wilcox, X.E. / Frumento, N. / Wright, D.A. / Paul, H.T. / Sinnis-Bourozikas, A. / Clark, K.E. / Figueroa, A. / Bjorkman, P.J. / Ray, S.C. / Flyak, A.I. / Bailey, J.R. |
External links | Immunity / PubMed:38518779 |
Methods | X-ray diffraction |
Resolution | 2.13 - 3.31 Å |
Structure data | PDB-8w0v: PDB-8w0w: PDB-8w0x: PDB-8w0y: |
Chemicals | ChemComp-NAG: ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM/VIRAL PROTEIN / HCV glycoprotein / broadly neutralizing antibodies / IMMUNE SYSTEM / IMMUNE SYSTEM-VIRAL PROTEIN complex |