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-Structure paper
Title | Broad protection against invasive fungal disease from a nanobody targeting the active site of fungal b-1,3-glucanosyltransferases. |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Page e202405823-e202405823, Year 2024 |
Publish date | Jun 13, 2023 (structure data deposition date) |
Authors | Redrado-Hernandez, S. / Macias-Leon, J. / Castro-Lopez, J. / Sanz, A.B. / Dolader, E. / Arias, M. / Gonzalez-Ramirez, A.M. / Sanchez-Navarro, D. / Petryk, Y. / Farkas, V. ...Redrado-Hernandez, S. / Macias-Leon, J. / Castro-Lopez, J. / Sanz, A.B. / Dolader, E. / Arias, M. / Gonzalez-Ramirez, A.M. / Sanchez-Navarro, D. / Petryk, Y. / Farkas, V. / Vincke, C. / Muyldermans, S. / Garcia-Barbazan, I. / Del Agua, C. / Zaragoza, O. / Arroyo, J. / Pardo, J. / Galvez, E. / Hurtado-Guerrero, R. |
External links | Angew. Chem. Int. Ed. Engl. / PubMed:38856634 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.05 Å |
Structure data | PDB-8pe1: PDB-8pe2: |
Chemicals | ChemComp-NAG: ChemComp-MAN: ChemComp-HOH: ChemComp-PO4: |
Source |
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Keywords | TRANSFERASE / Transglycosylase / b-1 / 3-glucan / nanobodies / fungal diseases |