+Search query
-Structure paper
Title | A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. |
---|---|
Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 62, Page e202310728-e202310728, Year 2023 |
Publish date | Jun 6, 2023 (structure data deposition date) |
Authors | Jiang, P. / Jin, H. / Zhang, G. / Zhang, W. / Liu, W. / Zhu, Y. / Zhang, C. / Zhang, L. |
External links | Angew. Chem. Int. Ed. Engl. / PubMed:37917570 |
Methods | X-ray diffraction |
Resolution | 2 - 2.25 Å |
Structure data | PDB-8jnc: PDB-8jno: PDB-8jnp: PDB-8jnq: PDB-8joo: PDB-8jua: |
Chemicals | ChemComp-HEM: ChemComp-E5I: ChemComp-FMT: ChemComp-NA: ChemComp-HOH: ChemComp-E8T: ChemComp-EIA: ChemComp-EIU: ChemComp-F7Z: |
Source |
|
Keywords | OXIDOREDUCTASE / hydroxylation / polycyclic tetramate macrolactam / cytochrome P450 / Actinomadura viridis / hydrolase / Lobophorin / deglycosylation / C-H functionalization / regioselectivity / chemoselectivity / polycyclic tetramate macrolactam (PoTeM) / cytochrome P450 enzyme |