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-Structure paper
Title | Structure-Guided Chemical Optimization of Bicyclic Peptide ( Bicycle ) Inhibitors of Angiotensin-Converting Enzyme 2. |
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Journal, issue, pages | J. Med. Chem., Vol. 66, Page 9881-9893, Year 2023 |
Publish date | Oct 6, 2022 (structure data deposition date) |
Authors | Harman, M.A.J. / Stanway, S.J. / Scott, H. / Demydchuk, Y. / Bezerra, G.A. / Pellegrino, S. / Chen, L. / Brear, P. / Lulla, A. / Hyvonen, M. ...Harman, M.A.J. / Stanway, S.J. / Scott, H. / Demydchuk, Y. / Bezerra, G.A. / Pellegrino, S. / Chen, L. / Brear, P. / Lulla, A. / Hyvonen, M. / Beswick, P.J. / Skynner, M.J. |
External links | J. Med. Chem. / PubMed:37433017 |
Methods | X-ray diffraction |
Resolution | 2.07 - 2.61 Å |
Structure data | PDB-8b9p: PDB-8bfw: PDB-8bn1: PDB-8byj: |
Chemicals | ChemComp-LFI: ChemComp-HOH: ChemComp-ZN: ChemComp-NA: |
Source |
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Keywords | MEMBRANE PROTEIN / Cov-2-sars bind proteins |