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-Structure paper
Title | Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27. |
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Journal, issue, pages | Cell Rep, Vol. 41, Page 111490-111490, Year 2022 |
Publish date | Apr 1, 2022 (structure data deposition date) |
Authors | Skladanowska, K. / Bloch, Y. / Strand, J. / White, K.F. / Hua, J. / Aldridge, D. / Welin, M. / Logan, D.T. / Soete, A. / Merceron, R. ...Skladanowska, K. / Bloch, Y. / Strand, J. / White, K.F. / Hua, J. / Aldridge, D. / Welin, M. / Logan, D.T. / Soete, A. / Merceron, R. / Murphy, C. / Provost, M. / Bazan, J.F. / Hunter, C.A. / Hill, J.A. / Savvides, S.N. |
External links | Cell Rep / PubMed:36261006 |
Methods | X-ray diffraction |
Resolution | 2.2 - 3.18 Å |
Structure data | PDB-7zg0: PDB-7zxk: |
Chemicals | ChemComp-NAG: ChemComp-HOH: |
Source |
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Keywords | CYTOKINE / receptor / heterodimer / cancer / glycoprotein / neutralizing / antibody |