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-Structure paper
Title | Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome. |
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Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 29, Page 966-977, Year 2022 |
Publish date | Feb 4, 2022 (structure data deposition date) |
![]() | Bonsor, D.A. / Alexander, P. / Snead, K. / Hartig, N. / Drew, M. / Messing, S. / Finci, L.I. / Nissley, D.V. / McCormick, F. / Esposito, D. ...Bonsor, D.A. / Alexander, P. / Snead, K. / Hartig, N. / Drew, M. / Messing, S. / Finci, L.I. / Nissley, D.V. / McCormick, F. / Esposito, D. / Rodriguez-Viciana, P. / Stephen, A.G. / Simanshu, D.K. |
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Methods | X-ray diffraction |
Resolution | 2.17 - 2.4 Å |
Structure data | ![]() PDB-7tvf: ![]() PDB-7tvg: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-MN: ![]() ChemComp-NA: ![]() ChemComp-PO4: ![]() ChemComp-CL: ![]() ChemComp-GNP: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
Source |
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![]() | SIGNALING PROTEIN / Oncoprotein Phosphatase Scaffold protein Adaptor RAS Leucine rich repeat / Scaffold protein Adapter protein Leucine rich repeat Oncoprotein |