+Search query
-Structure paper
Title | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA |
---|---|
Journal, issue, pages | To Be Published |
Publish date | Nov 25, 2021 (structure data deposition date) |
Authors | Brown ZP / Abaeva IS / De S / Hellen CUT / Pestova TV / Frank J |
External links | Search PubMed |
Methods | EM (single particle) |
Resolution | 3.7 - 4.6 Å |
Structure data | EMDB-25527, PDB-7syg: EMDB-25528, PDB-7syh: EMDB-25534, PDB-7syn: EMDB-25600: Map of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. eIF5B in position 1 EMDB-25601: Map of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. eIF5B in position 2 |
Chemicals | ChemComp-ZN: |
Source |
|
Keywords | RIBOSOME / HCV / IRES / 40S |