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-Structure paper
Title | The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3. |
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Journal, issue, pages | Commun Biol, Vol. 5, Page 954-954, Year 2022 |
Publish date | Dec 1, 2021 (structure data deposition date) |
Authors | Notova, S. / Bonnardel, F. / Rosato, F. / Siukstaite, L. / Schwaiger, J. / Lim, J.H. / Bovin, N. / Varrot, A. / Ogawa, Y. / Romer, W. ...Notova, S. / Bonnardel, F. / Rosato, F. / Siukstaite, L. / Schwaiger, J. / Lim, J.H. / Bovin, N. / Varrot, A. / Ogawa, Y. / Romer, W. / Lisacek, F. / Imberty, A. |
External links | Commun Biol / PubMed:36097056 |
Methods | X-ray diffraction |
Resolution | 1.7 - 2.2 Å |
Structure data | PDB-7qe3: PDB-7qe4: PDB-7r55: |
Chemicals | ChemComp-NGA: ChemComp-EDO: ChemComp-PEG: ChemComp-1JW: ChemComp-PGE: ChemComp-HOH: ChemComp-A2G: ChemComp-CL: ChemComp-NA: |
Source |
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Keywords | SUGAR BINDING PROTEIN / lectin / GalNAc / b-trefoil / pore forming lectin / Gb3 |