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Title | Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design. |
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Journal, issue, pages | J. Med. Chem., Vol. 64, Page 15334-15348, Year 2021 |
Publish date | Apr 28, 2021 (structure data deposition date) |
![]() | Li, X.P. / Harijan, R.K. / Cao, B. / Kahn, J.N. / Pierce, M. / Tsymbal, A.M. / Roberge, J.Y. / Augeri, D. / Tumer, N.E. |
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Methods | X-ray diffraction |
Resolution | 1.52 - 1.8 Å |
Structure data | ![]() PDB-7mln: ![]() PDB-7mlo: ![]() PDB-7mlp: ![]() PDB-7mlt: |
Chemicals | ![]() ChemComp-ZJA: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-ZJ7: ![]() ChemComp-EDO: ![]() ChemComp-SO4: ![]() ChemComp-ZJ4: ![]() ChemComp-ZN: ![]() ChemComp-CL: ![]() ChemComp-ZJD: |
Source |
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![]() | Hydrolase/Hydrolase Inhibitor / Ricin chain-A / RTA / Hydrolase / Toxin / Inhibitor / Hydrolase-Hydrolase Inhibitor complex |