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-Structure paper
Title | Discovery of a Pyrimidinedione Derivative with Potent Inhibitory Activity against Mycobacterium tuberculosis Ketol-Acid Reductoisomerase. |
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Journal, issue, pages | Chemistry, Vol. 27, Page 3130-3141, Year 2021 |
Publish date | Oct 9, 2020 (structure data deposition date) |
Authors | Lin, X. / Kurz, J.L. / Patel, K.M. / Wun, S.J. / Hussein, W.M. / Lonhienne, T. / West, N.P. / McGeary, R.P. / Schenk, G. / Guddat, L.W. |
External links | Chemistry / PubMed:33215746 |
Methods | X-ray diffraction |
Resolution | 2.59 - 2.63 Å |
Structure data | PDB-7ke2: PDB-7kh7: |
Chemicals | ChemComp-MG: ChemComp-WBY: ChemComp-HOH: ChemComp-NAP: ChemComp-NDP: |
Source |
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Keywords | ISOMERASE / Oxidoreductase / REDUCTOISOMERASE / INHIBITOR / METAL BINDING PROTEIN / ISOMERASE/Inhibitor / COMPLEX / ISOMERASE-Inhibitor complex |