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-Structure paper
Title | A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. |
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Journal, issue, pages | Cell Res., Vol. 33, Page 55-70, Year 2023 |
Publish date | Oct 9, 2020 (structure data deposition date) |
Authors | Liu, Z. / Chen, K. / Dai, J. / Xu, P. / Sun, W. / Liu, W. / Zhao, Z. / Bennett, S.P. / Li, P. / Ma, T. ...Liu, Z. / Chen, K. / Dai, J. / Xu, P. / Sun, W. / Liu, W. / Zhao, Z. / Bennett, S.P. / Li, P. / Ma, T. / Lin, Y. / Kawakami, A. / Yu, J. / Wang, F. / Wang, C. / Li, M. / Chase, P. / Hodder, P. / Spicer, T.P. / Scampavia, L. / Cao, C. / Pan, L. / Dong, J. / Chen, Y. / Yu, B. / Guo, M. / Fang, P. / Fisher, D.E. / Wang, J. |
External links | Cell Res. / PubMed:36588115 |
Methods | X-ray diffraction |
Resolution | 1.9 - 3.201 Å |
Structure data | PDB-7d8r: PDB-7d8s: PDB-7d8t: PDB-7eod: |
Chemicals | ChemComp-HOH: ChemComp-SO4: ChemComp-GOL: |
Source |
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Keywords | TRANSCRIPTION / TRANSCRIPTION FACTOR / TRANSCRIPTION/DNA / TRANSCRIPTION-DNA complex |