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Structure paper

TitleHeterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism.
Journal, issue, pagesPlos One, Vol. 16, Page e0251067-e0251067, Year 2021
Publish dateAug 5, 2020 (structure data deposition date)
AuthorsKwon, S. / Chun, H.L. / Ha, H.J. / Lee, S.Y. / Park, H.H.
External linksPlos One / PubMed:33951112
MethodsX-ray diffraction
Resolution2.58 Å
Structure data

PDB-7cp1:
Crystal structure of isocitrate lyase in complex with succinate and itaconate
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

Chemicals

ChemComp-SIN:
SUCCINIC ACID

ChemComp-MG:
Unknown entry

ChemComp-ITN:
2-methylidenebutanedioic acid

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis h37rv (bacteria)
KeywordsLYASE / Glyoxylate cycle / Isocitrate lyase / Succinate / Itaconate / Mycobacterium tuberculosis

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