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-Structure paper
Title | Molecular Mechanism of Selective Substrate Engagement and Inhibitor Dis-engagement of Cysteine Synthase. |
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Journal, issue, pages | J. Biol. Chem., Year 2020 |
Publish date | Mar 23, 2017 (structure data deposition date) |
![]() | Kaushik, A. / Rahisuddin, R. / Saini, N. / Singh, R.P. / Kaur, R. / Kaul, S. / Kumaran, S. |
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Methods | X-ray diffraction |
Resolution | 1.69 - 2.1 Å |
Structure data | ![]() PDB-5xcn: ![]() PDB-5xcp: ![]() PDB-5xcw: ![]() PDB-7c35: ![]() PDB-7cm8: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-NA: ![]() ChemComp-GOL: |
Source |
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![]() | TRANSFERASE / Pyridoxal phosphate binding / cysteine synthase activity / L-cysteine desulfhydrase activity / transferase activity / serine acetyl transferase interacting protein / O-acetylserine (thiol)-lyase / Interacts with Serine acetyl transferase / Serine acetyl transferase binding protein / PLP dependent enzyme / Cysteine metabolizing Enzyme / O acetyl transferase enzyme / Cysteine synthase / Substrate selection / mutant / Competetive allostery |