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-Structure paper
Title | A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations. |
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Journal, issue, pages | Elife, Vol. 9, Year 2020 |
Publish date | Aug 11, 2020 (structure data deposition date) |
Authors | Paesmans, J. / Martin, E. / Deckers, B. / Berghmans, M. / Sethi, R. / Loeys, Y. / Pardon, E. / Steyaert, J. / Verstreken, P. / Galicia, C. / Versees, W. |
External links | Elife / PubMed:33349335 |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.73 Å |
Structure data | PDB-7a0v: PDB-7a17: |
Chemicals | ChemComp-PO4: ChemComp-MG: ChemComp-GOL: ChemComp-HOH: ChemComp-IP9: |
Source |
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Keywords | HYDROLASE / Inositol polyphosphate 5-phosphatase / Phosphoinositide / Parkinson's disease / Epilepsy / Enzyme-substrate complex / Catalytic Mechanism |