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-Structure paper
Title | Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 117, Page 15620-15631, Year 2020 |
Publish date | May 20, 2020 (structure data deposition date) |
Authors | Malinauskas, T. / Peer, T.V. / Bishop, B. / Mueller, T.D. / Siebold, C. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:32576689 |
Methods | X-ray diffraction |
Resolution | 1.65 - 5.501 Å |
Structure data | PDB-6z3g: PDB-6z3h: PDB-6z3j: PDB-6z3l: PDB-6z3m: |
Chemicals | ChemComp-CIT: ChemComp-SO4: ChemComp-GOL: ChemComp-EDO: ChemComp-CL: ChemComp-NAG: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN / Repulsive Guidance Molecule / RGM / Bone Morphogenetic Protein / BMP / Growth Differentiation Factor 5 / GDF5 / Neogenin / axon guidance / TGFbeta signalling / brain development / iron metabolism. / iron metabolism / Hemojuvelin / HJV / HFE2 / hemochromatosis type 2 protein / juvenile hemochromatosis. |