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TitleStructure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.
Journal, issue, pagesStructure, Vol. 28, Page 1300-1312.e5, Year 2020
Publish dateMay 19, 2020 (structure data deposition date)
AuthorsBochel, A.J. / Williams, C. / McCoy, A.J. / Hoppe, H.J. / Winter, A.J. / Nicholls, R.D. / Harlos, K. / Jones, E.Y. / Berger, I. / Hassan, A.B. / Crump, M.P.
External linksStructure / PubMed:32877646
MethodsX-ray diffraction
Resolution1.5 - 3.47 Å
Structure data

PDB-6z30:
Human cation-independent mannose 6-phosphate/ IGF2 receptor domains 9-10
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-6z31:
Human cation-independent mannose 6-phosphate/ IGF2 receptor domain 8
Method: X-RAY DIFFRACTION / Resolution: 2.56 Å

PDB-6z32:
Human cation-independent mannose 6-phosphate/IGF2 receptor domains 7-11
Method: X-RAY DIFFRACTION / Resolution: 3.47 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsSUGAR BINDING PROTEIN / Mannose 6-phosphate / Cation-independent mannose 6-phosphate receptor / Insulin-like growth factor 2 receptor / P-type lectin

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