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TitleCrystal structure of PT2863 bound to HIF2a-B*:ARNT-B* complex
Journal, issue, pagesTo Be Published
Publish dateMay 20, 2020 (structure data deposition date)
AuthorsDu, X.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-6x2h:
Crystal structure of PT2863 bound to HIF2a-B*:ARNT-B* complex
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-ULD:
cis-3-({(1S)-7-[dihydroxy(trifluoromethyl)-lambda~4~-sulfanyl]-2,2-difluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl}oxy)cyclobutane-1-carbonitrile

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Hif2a / Pas B domain / ARNT / hypoxia inducible factor / EPAS1

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