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TitleEga3 from the fungal pathogenAspergillus fumigatusis an endo-alpha-1,4-galactosaminidase that disrupts microbial biofilms.
Journal, issue, pagesJ. Biol. Chem., Vol. 294, Page 13833-13849, Year 2019
Publish dateApr 10, 2019 (structure data deposition date)
AuthorsBamford, N.C. / Le Mauff, F. / Subramanian, A.S. / Yip, P. / Millan, C. / Zhang, Y. / Zacharias, C. / Forman, A. / Nitz, M. / Codee, J.D.C. ...Bamford, N.C. / Le Mauff, F. / Subramanian, A.S. / Yip, P. / Millan, C. / Zhang, Y. / Zacharias, C. / Forman, A. / Nitz, M. / Codee, J.D.C. / Uson, I. / Sheppard, D.C. / Howell, P.L.
External linksJ. Biol. Chem. / PubMed:31416836
MethodsX-ray diffraction
Resolution1.76 - 2.093 Å
Structure data

PDB-6oj1:
Crystal Structure of Aspergillus fumigatus Ega3
Method: X-RAY DIFFRACTION / Resolution: 1.76 Å

PDB-6ojb:
Crystal Structure of Aspergillus fumigatus Ega3 complex with galactosamine
Method: X-RAY DIFFRACTION / Resolution: 2.093 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-X6X:
2-amino-2-deoxy-alpha-D-galactopyranose

Source
  • neosartorya fumigata (strain atcc mya-4609 / af293 / cbs 101355 / fgsc a1100) (mold)
KeywordsHYDROLASE / galactosaminidase / (beta/alpha)-barrel / glycoside hydrolase

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