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-Structure paper
Title | Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase. |
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Journal, issue, pages | J. Med. Chem., Vol. 62, Page 7489-7505, Year 2019 |
Publish date | Apr 9, 2019 (structure data deposition date) |
![]() | Andrews, L.D. / Kane, T.R. / Dozzo, P. / Haglund, C.M. / Hilderbrandt, D.J. / Linsell, M.S. / Machajewski, T. / McEnroe, G. / Serio, A.W. / Wlasichuk, K.B. ...Andrews, L.D. / Kane, T.R. / Dozzo, P. / Haglund, C.M. / Hilderbrandt, D.J. / Linsell, M.S. / Machajewski, T. / McEnroe, G. / Serio, A.W. / Wlasichuk, K.B. / Neau, D.B. / Pakhomova, S. / Waldrop, G.L. / Sharp, M. / Pogliano, J. / Cirz, R.T. / Cohen, F. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.06 - 2.5 Å |
Structure data | ![]() PDB-6oi8: ![]() PDB-6oi9: |
Chemicals | ![]() ChemComp-EDO: ![]() ChemComp-MQV: ![]() ChemComp-HOH: ![]() ChemComp-MQM: |
Source |
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![]() | LIGASE / ATP GRASP / CARBOXYLASE / INHIBITOR / BIOTIN CARBOXYL CARRIER PROTEIN AND CARBOXYLTRANSFERASE |