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-Structure paper
Title | Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis. |
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Journal, issue, pages | J. Biol. Chem., Vol. 295, Page 3759-3770, Year 2020 |
Publish date | Feb 15, 2019 (structure data deposition date) |
Authors | Bashiri, G. / Nigon, L.V. / Jirgis, E.N.M. / Ho, N.A.T. / Stanborough, T. / Dawes, S.S. / Baker, E.N. / Bulloch, E.M.M. / Johnston, J.M. |
External links | J. Biol. Chem. / PubMed:32029475 |
Methods | X-ray diffraction |
Resolution | 2.35 - 3.03 Å |
Structure data | PDB-6o04: PDB-6o0g: PDB-6o0j: PDB-6o0n: |
Chemicals | ChemComp-DNA: ChemComp-ACT: ChemComp-FMT: ChemComp-MG: ChemComp-TOI: ChemComp-CL: ChemComp-HOH: ChemComp-AKG: ChemComp-TOG: ChemComp-PGE: ChemComp-GOL: ChemComp-TPP: |
Source |
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Keywords | transferase/transferase inhibitor / menaquinone biosynthesis / ThDP dependent / decarboxylation / C-C bond ligation / Inhibitor complex / SEPHCHC synthase / transferase-transferase inhibitor complex / MenD / TRANSFERASE |