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-Structure paper
Title | 15-deoxy-Delta12,14-Prostaglandin J2inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism. |
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Journal, issue, pages | Commun Biol, Vol. 2, Page 188-188, Year 2019 |
Publish date | Nov 13, 2018 (structure data deposition date) |
Authors | Abis, G. / Charles, R.L. / Kopec, J. / Yue, W.W. / Atkinson, R.A. / Bui, T.T.T. / Lynham, S. / Popova, S. / Sun, Y.B. / Fraternali, F. ...Abis, G. / Charles, R.L. / Kopec, J. / Yue, W.W. / Atkinson, R.A. / Bui, T.T.T. / Lynham, S. / Popova, S. / Sun, Y.B. / Fraternali, F. / Eaton, P. / Conte, M.R. |
External links | Commun Biol / PubMed:31123712 |
Methods | X-ray diffraction |
Resolution | 2 - 2.6 Å |
Structure data | PDB-6i5e: PDB-6i5g: |
Chemicals | ChemComp-HOH: ChemComp-EDO: ChemComp-PTG: |
Source |
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Keywords | HYDROLASE / hsEH CTD / apoprotein / alpha_beta hydrolase fold / 15d-PGJ2 |