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Title | Inhibition of BUB1 Kinase by BAY 1816032 Sensitizes Tumor Cells toward Taxanes, ATR, and PARP InhibitorsIn VitroandIn Vivo. |
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Journal, issue, pages | Clin. Cancer Res., Vol. 25, Page 1404-1414, Year 2019 |
Publish date | Dec 8, 2017 (structure data deposition date) |
Authors | Siemeister, G. / Mengel, A. / Fernandez-Montalvan, A.E. / Bone, W. / Schroder, J. / Zitzmann-Kolbe, S. / Briem, H. / Prechtl, S. / Holton, S.J. / Monning, U. ...Siemeister, G. / Mengel, A. / Fernandez-Montalvan, A.E. / Bone, W. / Schroder, J. / Zitzmann-Kolbe, S. / Briem, H. / Prechtl, S. / Holton, S.J. / Monning, U. / von Ahsen, O. / Johanssen, S. / Cleve, A. / Putter, V. / Hitchcock, M. / von Nussbaum, F. / Brands, M. / Ziegelbauer, K. / Mumberg, D. |
External links | Clin. Cancer Res. / PubMed:30429199 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-6f7b: |
Chemicals | ChemComp-CVQ: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / BUB1 / kinase inhibitor |