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-Structure paper
Title | Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction. |
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Journal, issue, pages | Cell Chem Biol, Vol. 26, Page 378-, Year 2019 |
Publish date | Jul 20, 2018 (structure data deposition date) |
Authors | Bum-Erdene, K. / Zhou, D. / Gonzalez-Gutierrez, G. / Ghozayel, M.K. / Si, Y. / Xu, D. / Shannon, H.E. / Bailey, B.J. / Corson, T.W. / Pollok, K.E. ...Bum-Erdene, K. / Zhou, D. / Gonzalez-Gutierrez, G. / Ghozayel, M.K. / Si, Y. / Xu, D. / Shannon, H.E. / Bailey, B.J. / Corson, T.W. / Pollok, K.E. / Wells, C.D. / Meroueh, S.O. |
External links | Cell Chem Biol / PubMed:30581134 |
Methods | X-ray diffraction |
Resolution | 2.43 Å |
Structure data | PDB-6e5g: |
Chemicals | ChemComp-HUY: ChemComp-HOH: |
Source |
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Keywords | TRANSCRIPTION/INHIBITOR / inhibitor / TRANSCRIPTION-INHIBITOR complex |