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TitleExpression system for structural and functional studies of human glycosylation enzymes.
Journal, issue, pagesNat. Chem. Biol., Vol. 14, Page 156-162, Year 2018
Publish dateAug 17, 2017 (structure data deposition date)
AuthorsMoremen, K.W. / Ramiah, A. / Stuart, M. / Steel, J. / Meng, L. / Forouhar, F. / Moniz, H.A. / Gahlay, G. / Gao, Z. / Chapla, D. ...Moremen, K.W. / Ramiah, A. / Stuart, M. / Steel, J. / Meng, L. / Forouhar, F. / Moniz, H.A. / Gahlay, G. / Gao, Z. / Chapla, D. / Wang, S. / Yang, J.Y. / Prabhakar, P.K. / Johnson, R. / Rosa, M.D. / Geisler, C. / Nairn, A.V. / Seetharaman, J. / Wu, S.C. / Tong, L. / Gilbert, H.J. / LaBaer, J. / Jarvis, D.L.
External linksNat. Chem. Biol. / PubMed:29251719
MethodsX-ray diffraction
Resolution2.35 - 3.1 Å
Structure data

PDB-6apj:
Crystal Structure of human ST6GALNAC2
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-6apl:
Crystal Structure of human ST6GALNAC2 in complex with CMP
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-C5P:
CYTIDINE-5'-MONOPHOSPHATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / glycosyltransferase / Structural Genomics / PSI-Biology / Northeast Structural Genomics Consortium / NESG

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