Title Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase. Journal, issue, pages Cell Chem Biol , Vol. 26, Page 936-, Year 2019Publish date Jul 18, 2018 (structure data deposition date) AuthorsYanagisawa, T. / Kuratani, M. / Seki, E. / Hino, N. / Sakamoto, K. / Yokoyama, S. External links Cell Chem Biol / PubMed:31031143Methods X-ray diffraction Resolution 1.368 - 1.842 Å Structure data PDB-6aac : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mAzZLys Method : X-RAY DIFFRACTION / Resolution : 1.479 Å
PDB-6aad : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mTmdZLys Method : X-RAY DIFFRACTION / Resolution : 1.444 Å
PDB-6aan : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mEtZLys Method : X-RAY DIFFRACTION / Resolution : 1.51 Å
PDB-6aao : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TCO*Lys Method : X-RAY DIFFRACTION / Resolution : 1.403 Å
PDB-6aap : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with ZaeSeCys Method : X-RAY DIFFRACTION / Resolution : 1.5 Å
PDB-6aaq : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with BCNLys Method : X-RAY DIFFRACTION / Resolution : 1.551 Å
PDB-6aaz : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pNO2ZLys Method : X-RAY DIFFRACTION / Resolution : 1.842 Å
PDB-6ab0 : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pAmPyLys Method : X-RAY DIFFRACTION / Resolution : 1.441 Å
PDB-6ab1 : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oAzZLys Method : X-RAY DIFFRACTION / Resolution : 1.381 Å
PDB-6ab2 : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oClZLys Method : X-RAY DIFFRACTION / Resolution : 1.4 Å
PDB-6ab8 : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with ZLys Method : X-RAY DIFFRACTION / Resolution : 1.753 Å
PDB-6abk : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TeocLys Method : X-RAY DIFFRACTION / Resolution : 1.58 Å
PDB-6abl : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oBrZLys Method : X-RAY DIFFRACTION / Resolution : 1.47 Å
PDB-6abm : Structure viewer Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pTmdZLys Method : X-RAY DIFFRACTION / Resolution : 1.368 Å
Chemicals ChemComp-ATP : Structure viewer ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM
ChemComp-9TR : Structure viewer N6-{[(3-azidophenyl)methoxy]carbonyl}-L-lysine
ChemComp-9TU : Structure viewer N6-[({3-[3-(trifluoromethyl)-3H-diaziren-3-yl]phenyl}methoxy)carbonyl]-L-lysine
ChemComp-9TX : Structure viewer N6-{[(3-ethynylphenyl)methoxy]carbonyl}-L-lysine
ChemComp-9U0 : Structure viewer N6-({[(1S,2E)-cyclooct-2-en-1-yl]oxy}carbonyl)-L-lysine
ChemComp-9U6 : Structure viewer 3-[(2-{[(benzyloxy)carbonyl]amino}ethyl)selanyl]-L-alanine
ChemComp-9U9 : Structure viewer N6-({[(1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl]methoxy}carbonyl)-L-lysine
ChemComp-9UC : Structure viewer N6-{[(4-nitrophenyl)methoxy]carbonyl}-L-lysine
ChemComp-9UF : Structure viewer N6-{[(6-aminopyridin-3-yl)methoxy]carbonyl}-L-lysine
ChemComp-9V0 : Structure viewer (2S)-2-azanyl-6-[(2-azidophenyl)methoxycarbonylamino]hexanoic acid
ChemComp-9V6 : Structure viewer (2S)-2-azanyl-6-[(2-chlorophenyl)methoxycarbonylamino]hexanoic acid
ChemComp-9VC : Structure viewer (2S)-2-azanyl-6-(phenylmethoxycarbonylamino)hexanoic acid
ChemComp-9VF : Structure viewer (2S)-2-azanyl-6-(trimethylsilylmethoxycarbonylamino)hexanoic acid
ChemComp-9VL : Structure viewer (2S)-2-azanyl-6-[(2-bromophenyl)methoxycarbonylamino]hexanoic acid
ChemComp-9VR : Structure viewer (2S)-2-azanyl-6-[[4-[3-(trifluoromethyl)-1,2-diazirin-3-yl]phenyl]methoxycarbonylamino]hexanoic acid
Source methanosarcina mazei jcm 9314 (archaea) Keywords TRANSLATION / aminoacyl-tRNA synthetase / non-natural amino acids / pyrrolysyl-tRNA synthetase / tRNA