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-Structure paper
Title | Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis. |
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Journal, issue, pages | J. Med. Chem., Vol. 62, Page 2564-2581, Year 2019 |
Publish date | Feb 26, 2018 (structure data deposition date) |
Authors | Malwal, S.R. / Chen, L. / Hicks, H. / Qu, F. / Liu, W. / Shillo, A. / Law, W.X. / Zhang, J. / Chandnani, N. / Han, X. ...Malwal, S.R. / Chen, L. / Hicks, H. / Qu, F. / Liu, W. / Shillo, A. / Law, W.X. / Zhang, J. / Chandnani, N. / Han, X. / Zheng, Y. / Chen, C.C. / Guo, R.T. / AbdelKhalek, A. / Seleem, M.N. / Oldfield, E. |
External links | J. Med. Chem. / PubMed:30730737 |
Methods | X-ray diffraction |
Resolution | 2.18 - 2.845 Å |
Structure data | PDB-5ze6: PDB-5zhe: PDB-5zlf: |
Chemicals | ChemComp-HJX: ChemComp-MG: ChemComp-HOH: ChemComp-B29: |
Source |
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Keywords | TRANSFERASE/INHIBITOR / PRENYLTRANSFERASE / SITE-DIRECTED MUTAGENESIS / PRODUCT CHAIN LENGTH / TRANSFERASE-INHIBITOR complex / metal-binding / substrate binding / acidocalcisomal pyrophosphatase |