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-Structure paper
Title | Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. |
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Journal, issue, pages | Nat Chem, Vol. 10, Page 599-606, Year 2018 |
Publish date | Jan 12, 2017 (structure data deposition date) |
![]() | Mousnier, A. / Bell, A.S. / Swieboda, D.P. / Morales-Sanfrutos, J. / Perez-Dorado, I. / Brannigan, J.A. / Newman, J. / Ritzefeld, M. / Hutton, J.A. / Guedan, A. ...Mousnier, A. / Bell, A.S. / Swieboda, D.P. / Morales-Sanfrutos, J. / Perez-Dorado, I. / Brannigan, J.A. / Newman, J. / Ritzefeld, M. / Hutton, J.A. / Guedan, A. / Asfor, A.S. / Robinson, S.W. / Hopkins-Navratilova, I. / Wilkinson, A.J. / Johnston, S.L. / Leatherbarrow, R.J. / Tuthill, T.J. / Solari, R. / Tate, E.W. |
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Methods | X-ray diffraction |
Resolution | 1.29 - 1.88 Å |
Structure data | ![]() PDB-5mu6: ![]() PDB-5o48: ![]() PDB-5o4v: ![]() PDB-5o6h: ![]() PDB-5o6j: |
Chemicals | ![]() ChemComp-MYA: ![]() ChemComp-MG: ![]() ChemComp-GOL: ![]() ChemComp-KFK: ![]() ChemComp-HOH: ![]() ChemComp-NHW: ![]() ChemComp-9K2: ![]() ChemComp-DMS: ![]() ChemComp-CL: ![]() ChemComp-SO4: ![]() ChemComp-9KZ: ![]() ChemComp-PO4: ![]() ChemComp-9M2: ![]() ChemComp-9M8: |
Source |
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![]() | TRANSFERASE / N-myristoylation / Inhibitor / Rhinovirus capsule assembly / MYRISTOYL |