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-Structure paper
Title | The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers. |
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Journal, issue, pages | Sci Rep, Vol. 6, Page 34303-34303, Year 2016 |
Publish date | Apr 29, 2016 (structure data deposition date) |
Authors | Dahms, S.O. / Creemers, J.W. / Schaub, Y. / Bourenkov, G.P. / Zogg, T. / Brandstetter, H. / Than, M.E. |
External links | Sci Rep / PubMed:27670069 |
Methods | X-ray diffraction |
Resolution | 1.998 - 2.27 Å |
Structure data | PDB-5jmo: PDB-5jmr: |
Chemicals | ChemComp-NAG: ChemComp-CA: ChemComp-NA: ChemComp-HOH: ChemComp-CL: |
Source |
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Keywords | Hydrolase/Antibody / protease / camelid / antibody / complex / Hydrolase-Antibody complex / furin / IMMUNE SYSTEM / inhibitor |