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TitleProtein Translation Enzyme lysyl-tRNA Synthetase Presents a New Target for Drug Development against Causative Agents of Loiasis and Schistosomiasis
Journal, issue, pagesPLoS Negl Trop Dis, Vol. 10, Page e0005084-e0005084, Year 2016
Publish dateJan 8, 2016 (structure data deposition date)
AuthorsSharma, A. / Sharma, M. / Yogavel, M.
External linksPLoS Negl Trop Dis / PubMed:27806050
MethodsX-ray diffraction
Resolution3.283 Å
Structure data

PDB-5hgq:
Loa loa Lysyl-tRNA synthetase in complex with Cladosporin.
Method: X-RAY DIFFRACTION / Resolution: 3.283 Å

Chemicals

ChemComp-LYS:
LYSINE

ChemComp-KRS:
cladosporin

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • loa loa (African eye worm)
KeywordsLIGASE/LIGASE INHIBITOR / Cladosporin / Lysine-tRNA synthetase / Loa loa / helminth parasites / LIGASE-LIGASE INHIBITOR complex

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