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-Structure paper
Title | CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common beta chain of the IL-3, GM-CSF and IL-5 receptors. |
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Journal, issue, pages | Mabs, Vol. 8, Page 436-453, Year 2016 |
Publish date | Sep 23, 2015 (structure data deposition date) |
![]() | Panousis, C. / Dhagat, U. / Edwards, K.M. / Rayzman, V. / Hardy, M.P. / Braley, H. / Gauvreau, G.M. / Hercus, T.R. / Smith, S. / Sehmi, R. ...Panousis, C. / Dhagat, U. / Edwards, K.M. / Rayzman, V. / Hardy, M.P. / Braley, H. / Gauvreau, G.M. / Hercus, T.R. / Smith, S. / Sehmi, R. / McMillan, L. / Dottore, M. / McClure, B.J. / Fabri, L.J. / Vairo, G. / Lopez, A.F. / Parker, M.W. / Nash, A.D. / Wilson, N.J. / Wilson, M.J. / Owczarek, C.M. |
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Methods | X-ray diffraction |
Resolution | 3.97 Å |
Structure data | ![]() PDB-5dwu: |
Chemicals | ![]() ChemComp-NAG: |
Source |
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![]() | IMMUNE SYSTEM / Fab complex / antigen recognition / therapeutic antibody |