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-Structure paper
Title | Molecular Blueprint of Allosteric Binding Sites in a Homologue of the Agonist-Binding Domain of the Alpha7 Nicotinic Acetylcholine Receptor. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 112, Page E2543-, Year 2015 |
Publish date | Jan 22, 2015 (structure data deposition date) |
Authors | Spurny, R. / Debaveye, S. / Farinha, A. / Veys, K. / Vos, A.M. / Gossas, T. / Atack, J. / Bertrand, S. / Bertrand, D. / Danielson, U.H. ...Spurny, R. / Debaveye, S. / Farinha, A. / Veys, K. / Vos, A.M. / Gossas, T. / Atack, J. / Bertrand, S. / Bertrand, D. / Danielson, U.H. / Tresadern, G. / Ulens, C. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:25918415 |
Methods | X-ray diffraction |
Resolution | 2.149 - 2.85 Å |
Structure data | PDB-5afh: PDB-5afj: PDB-5afk: PDB-5afl: PDB-5afm: PDB-5afn: |
Chemicals | ChemComp-L0B: ChemComp-HOH: ChemComp-NAG: ChemComp-42R: ChemComp-GOL: ChemComp-BMA: ChemComp-MAN: ChemComp-5VU: ChemComp-TLA: ChemComp-FHV: ChemComp-9Z0: ChemComp-OJD: |
Source |
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Keywords | TRANSPORT PROTEIN / PENTAMERIC LIGAND-GATED ION CHANNELS / CYS-LOOP RECEPTOR / NICOTINIC ACETYLCHOLINE RECEPTOR / ALLOSTERIC MODULATION / DRUG DISCOVERY |