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-Structure paper
Title | LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor. |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 54, Page 6217-6221, Year 2015 |
Publish date | Apr 5, 2015 (structure data deposition date) |
![]() | Clark, P.G. / Vieira, L.C. / Tallant, C. / Fedorov, O. / Singleton, D.C. / Rogers, C.M. / Monteiro, O.P. / Bennett, J.M. / Baronio, R. / Muller, S. ...Clark, P.G. / Vieira, L.C. / Tallant, C. / Fedorov, O. / Singleton, D.C. / Rogers, C.M. / Monteiro, O.P. / Bennett, J.M. / Baronio, R. / Muller, S. / Daniels, D.L. / Mendez, J. / Knapp, S. / Brennan, P.E. / Dixon, D.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.8 - 1.95 Å |
Structure data | ![]() PDB-4z6h: ![]() PDB-4z6i: |
Chemicals | ![]() ChemComp-4L2: ![]() ChemComp-HOH: ![]() ChemComp-4L3: |
Source |
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![]() | TRANSCRIPTION / lysine-acetylated histone binding / chromatin regulator / Bromodomain / Structural Genomics / Structural Genomics Consortium / SGC |